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2009 Fiscal Year Final Research Report

Application of the Er : YAG laser for periodontal therapy and clarification of the biological effects

Research Project

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Project/Area Number 19592382
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Periodontal dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

AOKI Akira  Tokyo Medical and Dental University, 医歯学総合研究科, 助教 (30302889)

Co-Investigator(Kenkyū-buntansha) WATANABE Hisashi  東京医科歯科大学, 医歯学総合研究科, 准教授 (40143606)
ODA Shigeru  東京医科歯科大学, 医歯学総合研究科, 講師 (70160869)
KOBAYASHI Hiroaki  東京医科歯科大学, 歯学部, 助教 (50396967)
IWASAKI Kengo  東京女子医科大学, 医学部, 助教 (40401351)
TAKEUCHI Yasuo  東京医科歯科大学, 歯学部, 助教 (60396968)
AKIZUKI Tatsuya  東京医科歯科大学, 歯学部, 医員 (50401378)
MIZUTANI Koji  東京医科歯科大学, 歯学部, 医員 (60451910)
Co-Investigator(Renkei-kenkyūsha) ABIKO Yoshimitsu  日本大学松戸, 歯学部, 教授 (70050086)
Research Collaborator FRANK Schwarz  ドイツ,ハインリッヒ・ハイン大学, 歯学部, 準教授
ANTON Sculean  スイス,ベルン大学, 歯学部, 教授
CARLOS Eduard  ブラジル,サンパウロ大学, 歯学部, 教授
TAKASAKI Aristeo A  東京医科歯科大学, 医歯学総合研究科, 外国人研究者
VERICA Aleksic  東京医科歯科大学, 医歯学総合研究科・大学院
TANIGUCHI Yoichi  東京医科歯科大学, 医歯学総合研究科・大学院
Project Period (FY) 2007 – 2009
Keywords歯学 / 歯周外科学 / レーザー / 歯周炎 / 歯周治療 / インプラント / 細胞・組織 / 再生医学
Research Abstract

A new protocol for periodontal pocket treatment combining the use of conventional tools and the Er : YAG laser was established. Regarding surgical treatment of peri-implantitis, debridement using the Er : YAG laser was effective and increased new bone formation was observed after laser treatment in an animal study. Low level Er : YAG laser irradiation enhanced the proliferation of osteoblasts.

  • Research Products

    (42 results)

All 2010 2009 2008 2007

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (28 results) Book (2 results)

  • [Journal Article] Impact of laser application to support periodontal and peri-implant wound healing2009

    • Author(s)
      Schwarz F, Aoki A, Sculean A, Becker J.
    • Journal Title

      Periodontology 2000 51

      Pages: 79-108

    • Peer Reviewed
  • [Journal Article] Application of Antimicrobial Photodynamic Therapy in Periodontal and Peri-implant Diseases2009

    • Author(s)
      Takasaki AA, Aoki A, Mizutani K, Schwarz F, Sculean A, Wang C-Y, Koshy G, Romanos G, Ishikawa I, Izumi Y.
    • Journal Title

      Periodontology 2000 51

      Pages: 109-140

    • Peer Reviewed
  • [Journal Article] Application of lasers in periodontics-true Innovation or Myth?2009

    • Author(s)
      Ishikawa I, Aoki A, Takasaki AA, Mizutani K, Sasaki KM, Izumi Y.
    • Journal Title

      Periodontology 2000 50(1)

      Pages: 90-126

    • Peer Reviewed
  • [Journal Article] Energy Output Reduction and Surface Alteration of Quartz and Sapphire Tips Following Er:YAG Laser Contact Irradiation for Tooth Enamel Ablation2009

    • Author(s)
      Eguro T, Aoki A, Maeda T, Takasaki AA, Hasegaw M, Ogawa M, Suzuki T, Yonemoto K, Ishikawa I, Izumi Y, Katsuumi I.
    • Journal Title

      Lasers in Surgery and Medicine 41

      Pages: 595-604

    • Peer Reviewed
  • [Journal Article] Long-term Histologic Analysis of Bone Tissue Alteration and Healing Following Er:YAG Laser Irradiation Compared to Electrosurgery2009

    • Author(s)
      Yoshino T, Aoki A, Oda S, Takasaki AA, Mizutani K, Sasaki KM, Kinoshita A, Watanabe H, Ishikawa I, Izumi Y.
    • Journal Title

      Journal of Periodontology 80(1)

      Pages: 82-92

    • Peer Reviewed
  • [Journal Article] Laser application in non-surgical periodontal therapy : a systematic review2008

    • Author(s)
      Schwarz F, Aoki A, Becker J, Sculean A.
    • Journal Title

      Journal of Clinical Periodontology 35(s8)

      Pages: 29-44

    • Peer Reviewed
  • [Journal Article] Current status of clinical laser applications in periodontal therapy2008

    • Author(s)
      Aoki A, Mizutani K, Takasaki AA, Sasaki KM, Nagai S, Schwarz F, Yoshida I, Eguro T, Zeredo JL, Izumi Y.
    • Journal Title

      General Dentistry 56(7)

      Pages: 674-687

    • Peer Reviewed
  • [Journal Article] Clinical application of erbium:YAG laser in periodontology2008

    • Author(s)
      Ishikawa I, Aoki A, Takasaki AA.
    • Journal Title

      Journal of International Academy of Periodontology 10(1)

      Pages: 22-30

    • Peer Reviewed
  • [Journal Article] The effect of chemical and/or mechanical conditioning on the Er:YAG laser-treated root cementum : analysis of surface morphology and periodontal ligament fibroblast attachment2008

    • Author(s)
      Maruyama H, Aoki A, Sasaki KM, Takasaki AA, Iwasaki K, Ichinose S, Oda S, Ishikawa I, Izumi Y.
    • Journal Title

      Lasers in Surgery and Medicine 40(3)

      Pages: 211-222

    • Peer Reviewed
  • [Journal Article] Esthetic treatment of gingival melanin hyperpigmentation with Er:YAG laser : short-term clinical observations and patient follow-up2007

    • Author(s)
      Rosa DS, Aranha AC, Eduardo Cde P, Aoki A.
    • Journal Title

      Journal of Periodontology 78(10)

      Pages: 2018-25

    • Peer Reviewed
  • [Journal Article] Er:YAG laser therapy for peri-implant infection : a histological study2007

    • Author(s)
      Takasaki AA, Aoki A, Mizutani K, Kikuchi S, Oda S, Ishikawa I.
    • Journal Title

      Lasers in Medical Science 22

      Pages: 143-157

    • Peer Reviewed
  • [Journal Article] Immunohistochemical Characterization of Periodontal Wound Healing Following Nonsurgical Treatment With Fluorescence Controlled Er:YAG Laser Radiation in Dogs2007

    • Author(s)
      Schwarz F, Jepsen S, Herten M, Aoki A, Sculean A, Becker J.
    • Journal Title

      Lasers in Surgery and Medicine 39

      Pages: 428-440

    • Peer Reviewed
  • [Presentation] Low-level Er:YAG laser irradiation enhances osteoblast proliferation through activation of MAPK/ERK2010

    • Author(s)
      Aleksic V, Aoki A, Iwasaki K, Takasaki AA, Wang C-Y, Abiko Y, Ishikawa I, Izumi Y.
    • Organizer
      The 12th congress of the World Federation for lasers Dentistry (WFLD)
    • Place of Presentation
      Dubai
    • Year and Date
      20100309-20100311
  • [Presentation] Determination of optimal irradiation parameters for debridement of micro-structured surface of titanium implant with a high-pulse-rate Er:YAG laser2010

    • Author(s)
      Taniguchi Y, Aoki A, Mizutani K, Takeuchi Y, Takasaki AA, Y. Izumi Y.
    • Organizer
      The 12th congress of the World Federation for lasers Dentistry (WFLD)
    • Place of Presentation
      Dubai
    • Year and Date
      20100309-20100311
  • [Presentation] Low-level Er:YAG laser irradiation can enhance proliferation of osteoblasts2009

    • Author(s)
      Aleksic V, Aoki A, Iwasaki K, Takasaki AA, Izumi Y.
    • Organizer
      6th Congress of the European Federation of Periodontology (Europerio 6)
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      20090604-20090606
  • [Presentation] Er:YAGレーザーの歯周病罹患根面に対する除菌効果2009

    • Author(s)
      穐山文彦, 青木章, 和泉雄一
    • Organizer
      第74回口腔病学会学術大会
    • Place of Presentation
      東京医科歯科大学, 東京
    • Year and Date
      2009-12-05
  • [Presentation] Er:YAGレーザーによるフラップレス骨整形2009

    • Author(s)
      水谷幸嗣, 青木章, 谷口陽一, 和泉雄一
    • Organizer
      第21回日本レーザー歯学会総会・学術大会
    • Place of Presentation
      福岡県歯科医師会館, 福岡
    • Year and Date
      2009-11-22
  • [Presentation] Low-level Er:YAG laser irradiation can enhance proliferation of osteoblasts2009

    • Author(s)
      アレクシチヴェリツァ, 青木章, 岩崎剣吾, 王振頴, 和泉雄一
    • Organizer
      第52回春季日本歯周病学会学術大会
    • Place of Presentation
      岡山, 岡山コンベンションセンター
    • Year and Date
      2009-05-16
  • [Presentation] The bactericidal effect of blue lights on a periodontal pathogen2009

    • Author(s)
      Aoki A, Namiki N, Takasaki AA, Sasaki KM, Mizutani K, Takagi C, Yoshino J, Umeda M, Watanabe H, Ishikawa I, Izumi Y.
    • Organizer
      Academy of Laser Dentistry 16th Annual Conference
    • Place of Presentation
      Las Vegas, Nevada, USA
    • Year and Date
      2009-04-23
  • [Presentation] 骨組織に対するEr:YAGレーザー照射後の長期組織学的観察2008

    • Author(s)
      吉野敏明, 青木章, 小田茂, 高崎アリステオ淳志, 水谷幸嗣, 木下淳博, 渡辺久, 石川烈, 和泉雄一
    • Organizer
      第20回日本レーザー歯学会総会・学術大会
    • Place of Presentation
      大阪, 大阪大学
    • Year and Date
      20080920-20080921
  • [Presentation] Successful management of gingival enlargement using lasers in a patient with a serious systemic disease : a case report2008

    • Author(s)
      Izumi Y, K. Mizutani K, Takasaki AA, Ohnishi H, Suda T, Aoki A.
    • Organizer
      11th Congress of World Federation for Laser Dentistry
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      20080728-20080730
  • [Presentation] Effect of high pulse rate Er:YAG laser irradiation using a chisel tip on subgingival calculus removal in vitro2008

    • Author(s)
      Mizutani K, Aoki A, Takasaki AA, Maruyama H, Schwarz F, Yamada T, Ichinose S, Ishikawa I, Izumi Y.
    • Organizer
      11th Congress of World Federation for Laser Dentistry
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      20080728-20080730
  • [Presentation] The effect of chemical and/or mechanical conditioning on the Er:YAG laser-treated root cementum : Analysis of surface morphology and periodontal ligament fibroblast attachment2008

    • Author(s)
      Maruyama H, Aoki A, Sasaki KM, Takasaki AA, Iwasaki K, Ichinose S, Oda S, Ishikawa I, Izumi Y.
    • Organizer
      11th Congress of World Federation for Laser Dentistry
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      20080728-20080730
  • [Presentation] Clinical evaluation of high pulse rate Er:YAG laser application in periodontal flap surgery2008

    • Author(s)
      Takasaki AA, Aoki A, Mizutani K, Akizuki T, Kobayashi H, Oda S, Watanabe H, Umeda M, Ishikawa I, Izum Y.
    • Organizer
      11th Congress of World Federation for Laser Dentistry
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      20080728-20080730
  • [Presentation] チゼル型チップを用いた高パルスEr:YAGレーザー照射による歯石除去効果2008

    • Author(s)
      水谷幸嗣, 青木章, 高崎アリステオ淳志, 丸山裕昭, 和泉雄一
    • Organizer
      日本歯科保存学会2008年春季学術大会 (第128回)
    • Place of Presentation
      新潟
    • Year and Date
      20080605-20080606
  • [Presentation] チゼル型チップを用いた高パルスEr:YAGレーザー照射による歯石除去効果2008

    • Author(s)
      水谷幸嗣, 青木章, 丸山裕昭, 和泉雄一
    • Organizer
      第73回口腔病学会学術大会
    • Place of Presentation
      東京医科歯科大学, お茶の水, 東京
    • Year and Date
      2008-12-05
  • [Presentation] Er:YAGレーザーの歯周治療への臨床応用2008

    • Author(s)
      青木章, 水谷幸嗣, 和泉雄一
    • Organizer
      第21回日本歯科医学会総会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2008-11-15
  • [Presentation] レーザーの Biostimulation 効果のメカニズムに関する研究2008

    • Author(s)
      渡辺久, 青木章, 和泉雄一
    • Organizer
      日第21回日本歯科医学会総会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2008-11-15
  • [Presentation] チゼルチップを用いたEr:YAGレーザーによるメラニン除去2008

    • Author(s)
      青木章, 水谷幸嗣, 高崎アリステオ淳志, 石井さやか, Verica Aleksic, Chen-Ying Wang, 和泉雄一
    • Organizer
      第20回日本レーザー歯学会総会・学術大会
    • Place of Presentation
      大阪, 大阪大学
    • Year and Date
      2008-09-20
  • [Presentation] 薬物性歯肉増殖を伴う慢性歯周炎の治療にレーザーを併用した一症例2008

    • Author(s)
      和泉雄一, 水谷幸嗣, 高崎アリステオ淳志, 青木章
    • Organizer
      第20回日本レーザー歯学会総会・学術大会
    • Place of Presentation
      大阪, 大阪大学
    • Year and Date
      2008-09-20
  • [Presentation] Long-term Histological Analysis of Bone Tissue Alteration and Healing Following Er:YAG Laser Irradiation in Comparison with Electrosurgery2008

    • Author(s)
      Yoshino T, Aoki A, Oda S, Takasaki AA, Mizutani K, Sasaki KM, Kinoshita A, Watanabe H, Ishikawa I, Izumi Y.
    • Organizer
      11th Congress of World Federation for Laser Dentistry
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2008-07-30
  • [Presentation] The effect of the pulse duration of Er:YAG laser on bone ablation2008

    • Author(s)
      Yanagiuchi Y, Aoki A, Gutknecht N, Ito A, Ishikawa I, Izumi Y.
    • Organizer
      11th Congress of World Federation for Laser Dentistry
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2008-07-30
  • [Presentation] 高パルスEr:YAGレーザーの歯周フラップ手術への臨床応用2007

    • Author(s)
      高崎アリステオ淳志, 青木章, 水谷幸嗣, 秋月達也, 小林宏明, 小田茂, 渡辺久, 梅田誠, 石川烈, 和泉雄一
    • Organizer
      第19回日本レーザー歯学会総会・学術大会
    • Place of Presentation
      横浜, 鶴見大学
    • Year and Date
      2007-11-23
  • [Presentation] フラップ手術における高パルスEr:YAGレーザーの応用の臨床的評価2007

    • Author(s)
      青木章, 高崎アリステオ淳志, 水谷幸嗣, 秋月達也, 小林宏明, 小田茂, 渡辺久, 石川烈, 和泉雄一
    • Organizer
      日本歯周病学会50周年記念大会
    • Place of Presentation
      東京国際フォーラム, 東京
    • Year and Date
      2007-09-22
  • [Presentation] インプラント周囲炎の外科的治療へのEr:YAGレーザーの応用に関する組織学的研究2007

    • Author(s)
      高崎アリステオ淳志, 青木章, 水谷幸嗣, 菊池重成, 小田茂, 石川烈, 和泉雄一
    • Organizer
      第37会 (社) 日本口腔インプラント学会学術大会
    • Place of Presentation
      熊本市市民会館, 熊本
    • Year and Date
      2007-09-15
  • [Presentation] インプラント周囲炎の外科的治療におけるEr:YAGレーザーの応用2007

    • Author(s)
      高崎アリステオ淳志, 青木章, 水谷幸嗣, 菊池重成, 小田茂, 石川烈, 和泉雄一
    • Organizer
      第10回Er:YAGレーザー臨床研究会
    • Place of Presentation
      京都, 国立京都国際会館
    • Year and Date
      2007-07-28
  • [Presentation] Innovative treatment of dental caries and periodontitis using Er:YAG Laser2007

    • Author(s)
      Aoki A.
    • Organizer
      2007 Congress of Asia Pasific Laser Institute
    • Place of Presentation
      Grand Hotel Taipei, Taiwan
    • Year and Date
      2007-07-21
  • [Presentation] Photo-bio-modulation Laser Strategies in Periodontal Therapy2007

    • Author(s)
      Aoki A.
    • Organizer
      ECI conference "Light-Activated Tissue Regeneration and Therapy II"
    • Place of Presentation
      Tomar, Portugal
    • Year and Date
      2007-06-27
  • [Presentation] Er:YAG laser in periodontics and implant dentistry2007

    • Author(s)
      Aoki A.
    • Organizer
      International dental laser symposium Fotona (2007 IDLS Fotona)
    • Place of Presentation
      Samsung COEX conference center, Seoul, Korea
    • Year and Date
      2007-04-22
  • [Presentation] レーザーによるう蝕・歯周治療の革新2007

    • Author(s)
      青木章, 大槻昌幸, 加藤純二, 渡辺久, 田上順次, 石川烈
    • Organizer
      レーザー学会学術講演会第27回年次大会
    • Place of Presentation
      宮崎, 宮崎市フェニックスシーガイアリゾート
    • Year and Date
      2007-01-18
  • [Book] Peri-implant Infection : Etiology, Diagnosis and Treatment(Schwarz F and Becker J.)2009

    • Author(s)
      Schwarz F, Takasaki A, Aoki A, Sager M, Becker J.
    • Total Pages
      191-195
  • [Book] Proceedings of Light-Activated Tissue Regeneration and Therapy Conference(Waynant R, Tata DB (Eds))2008

    • Author(s)
      Aoki A, Takasaki AA, Pourzarandian A, Mizutani K, Ruwanpura SMPM, Iwasaki K, Noguchi K, Oda S, Watanabe H, Ishikawa I, Izumi Y.
    • Total Pages
      181-190
    • Publisher
      Springer

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Published: 2011-06-18   Modified: 2016-04-21  

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