Rejuvenation with oral aging analysis

2010 Fiscal Year Final Research Report

• Project/Area Number: 19592414
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Tokyo Dental College
• Principal Investigator: MATSUZAKA Kenichi Tokyo Dental College, 歯学部, 准教授 (70266568)
• Co-Investigator(Kenkyū-buntansha): YOSHINARI Masao 東京歯科大学, 歯学部, 教授 (10085839) ; ISHIHARA Kazuyuki 東京歯科大学, 歯学部, 教授 (00212910) ; INOUE Takashi 東京歯科大学, 歯学部, 教授 (20125008)
• Project Period (FY): 2007 – 2010
• Keywords: 老年歯科学

Research Abstract

Although morphological and functional changes with age cannot be kept away, environment factors play an important role for controlling the excessive changes. This study revealed that excessive changes with age could be regulated using the controlling of environment factors.

Research Products

• [Journal Article] Effects of epidermal growth factor and/or nerve growth factor on Malassez's epithelial rest cells in vitro : mRNA expression of osteopontin (2010)
  • Author(s): Yamawaki K., Matsuzaka K., Kokubu E., Inoue T.
  • Journal Title: BMP-2 and VEGF,J Periodont Res 45 Pages: 421-427
  • Peer Reviewed
• [Journal Article] Responces of immature dental pulp under hypoxic conditions in vitro (2010)
  • Author(s): Senzui S., Matsuzaka K., Fukuhara F., Shintani S., Inoue T.
  • Journal Title: Oral Med Pathol 14 Pages: 107-111
  • Peer Reviewed
• [Journal Article] Age-related differences in the expression of heat shock protein 27 by rat periodontal ligament cells in culture (2010)
  • Author(s): Matsuzaka K., Kokubu E., Ito F., Ishida S., Endoh T., Katakura A., Yoshinari M., Inoue T.
  • Journal Title: Oral Med Pathol 14 Pages: 131-134
  • Peer Reviewed
• [Journal Article] Effect of mechanical loading on cultured osteogenic cells derived from different stages of bone wound healing in rats : experimental models for immediate or early loading implant models (2010)
  • Author(s): Sato D., Matsuzaka K., Kokubu E., Inoue T.
  • Journal Title: Oral Med Pathol 14 Pages: 143-151
  • Peer Reviewed
• [Journal Article] Effects of nicotine on Malassez' epithelial rest cells in early primary culture : cell proliferation and mRNA expression of heat shock protein 70 and vascular endothelial growth factor. (2009)
  • Author(s): Nakagawa E., Matsuzaka K., Naruse S., Naito K., Inoue T.
  • Journal Title: Oral Med Pathol 13 Pages: 41-45
  • Peer Reviewed
• [Journal Article] Mechanical force promotes proliferation and early differentiation of bone marrow derived osteoblast-like cells in vitro. (2009)
  • Author(s): Naito K., Matsuzaka K, Ishigami K., Inoue T.
  • Journal Title: Oral Med Pathol 13 Pages: 151-157
  • Peer Reviewed
• [Journal Article] Molecular and morphological analyses of the osteogenic activity of rat cultured periosteum cells in vivo and in vivo (2009)
  • Author(s): Soumiya H., Matsuzaka K., Shibahara T., Inoue T.
  • Journal Title: Oral Med Pathol 14 Pages: 19-28
  • Peer Reviewed
• [Journal Article] Changes in the homeostatic mechanism of dental pulp with age : Expression of CBFA-1, dentin sialoprotein (2008)
  • Author(s): Matsuzaka K., Muramatsu T., Katakukra A., Ishihara K., Hashimoto S., Yoshinari M., Endo T., Tazaki M., Shintani M., Sato Y., Inoue T.
  • Journal Title: VEGF and HSP-27 mRNAs,J Endodontics 34(7) Pages: 818-821
  • Peer Reviewed
• [Journal Article] Effect on the amount of bone-implant contact when splinting immediate-loaded dental implants (2007)
  • Author(s): Matsuzaka K., Nakajima T., Soejima Y., Kido, H., Matsuura M., Inoue T.
  • Journal Title: Implant Dentistry 16,(3) Pages: 309-316
  • Peer Reviewed
• [Journal Article] Characteristics of newly formed bone during guided bone regeneration Analysis of Cbfa-1 (2007)
  • Author(s): Tanaka S., Matsuzaka K., Sato D., Inoue T.
  • Journal Title: osteocalcin, and VEGF expression, JOral Implantology 33(6) Pages: 321-326
  • Peer Reviewed
• [Remarks] ホームページ等