2009 Fiscal Year Final Research Report
Innovative nano-therapy based on nanocarriers equipped with the ability to circumvent biological barriers
Project/Area Number |
19680026
|
Research Category |
Grant-in-Aid for Young Scientists (A)
|
Allocation Type | Single-year Grants |
Research Field |
Biomedical engineering/Biological material science
|
Research Institution | The University of Tokyo |
Principal Investigator |
NISHIYAMA Nobuhirp The University of Tokyo, 大学院・医学系研究科, 准教授 (10372385)
|
Project Period (FY) |
2007 – 2009
|
Keywords | ドラッグデリバリー / 高分子ミセル / がん治療 / 生体内バリア / 光エネルギー |
Research Abstract |
To realize the targeting therapy against intractable tumors such as pancreatic tumors and molecular cancer therapy using nucleic acids, we developed novel nanocarriers based on polymeric micelles, which can avoid biological barriers at the tissue and organelle levels and function responding to environmental changes or physical stimuli, by engineering functional polymeric materials. The usefulness of such nanocarriers has been demonstrated by in vitro and in vivo experiments.
|
Research Products
(30 results)