2010 Fiscal Year Final Research Report
Study on screening of novel healthy functional compounds from food materials
| Project/Area Number |
19680031
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Kobe Gakuin University |
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Principal Investigator |
MIZUSINA Yosiyuki Kobe Gakuin University, 栄養学部, 准教授 (20307705)
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| Project Period (FY) |
2007 – 2010
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| Keywords | 食品由来成分 / 栄養素 / DNA合成酵素 / 酵素阻害剤 / 抗がん活性 / 抗炎症活性 / 健康機能性食品 |
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| Research Abstract |
It was investigated and analyzed the effect of foods and nutrients on the inhibition of mammalian DNA polymerase (pol) species, anti-cancer and anti-inflammation. The glycolipids from spinach inhibited the activities of DNA replicative pols and showed anti-tumor activity. The curcumin derivatives showed specific inhibition of pol λ, which is a DNA repair and recombination related pol, and anti-inflammation.
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