2009 Fiscal Year Final Research Report
Production of useful compounds by means of molecular breeding of oleaginous fungi and unique microbial metabolism
| Project/Area Number |
19688006
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied microbiology
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| Research Institution | Kyoto University |
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Principal Investigator |
SAKURADANI Eiji Kyoto University, 農学研究科, 助教 (10362427)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 発酵生産 / 分子育種 / アルカン / 高度不飽和脂肪酸 / デスモステロール |
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| Research Abstract |
Oleaginous fungus Mortierella alpina 1S-4 produces various polyunsaturated fatty acids such as arachidonic acid. The researcher worked on development of homologous recombination in this strain, functional analysis of enzyme genes involved in polyunsaturated fatty acids, PUFA production through molecular breeding, elucidation of sterol biosynthetic pathways, and study on sub-terminal oxidation mechanism of n-alkanes. The results are considered not only to be directly connected with the field of microbial lipid production but also to be important to elucidate the mechanism of microbial lipid metabolism.
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