2009 Fiscal Year Final Research Report
A method for exhaustive similarity search of genomic positional expression.
| Project/Area Number |
19700275
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | Osaka University |
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Principal Investigator |
SENO Shigeto Osaka University, 大学院・情報科学研究科, 助教 (30432462)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 生物情報学 / 類似構造探索 / トランスクリプトーム解析 / 発現プロファイル / ゲノム |
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| Research Abstract |
I carried out analyses of gene expression patterns using the cap analysis gene expression (CAGE) method for exploring systematic views of tanscriptomes. Counting the number of mapped CAGE tags for fixed-length regions allows determination of the genomic expression levels. I developed a novel algorithm which provides a novel view to the genome from the genomic positional expression, and also developed a method based on graph algorithm and statistical approach for discovering tissue-specific regulation of alternative transcripts through a genome-wide analysis.
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