2008 Fiscal Year Final Research Report
Design of surface modification on the chip for high performance surface plasmon resonance biosensing
| Project/Area Number |
19700410
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
内田 勝美 Tokyo University of Science, 理学部, 嘱託助教 (50385514)
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| Project Period (FY) |
2007 – 2008
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| Keywords | 温度応答性高分子 / バイオセンシング / シグナル増幅効果 |
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| Research Abstract |
Detection of the specific interaction between biomacromolecules with surface plasmon resonance (SPR) measurements is to utilize the change of the refractive index induced by binding between biomacromolecules. In this study, we utilized thermo-responsive polymeric micelle for SPR biosensing, resulting in amplification of SPR signal by the phase transition of the micelle that induced by binding to biomacromolecule.
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