2009 Fiscal Year Final Research Report
Molecular aspects for heat stress-associated muscle hypertrophy
| Project/Area Number |
19700451
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Toyohashi Sozo University |
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Principal Investigator |
OHNO Yoshitaka Toyohashi Sozo University, 保健医療学部, 助教 (80440808)
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| Project Period (FY) |
2007 – 2009
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| Keywords | リハビリテーション医学 |
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| Research Abstract |
Molecular mechanism for muscle hypertrophy in response to heat stress is still unclear. In the present study, the molecular responses of skeletal muscles to heat stress were investigated in experimental animals and cultured skeletal muscle cells. Results demonstrated that nuclear factor-Kβ signaling would be, in part, involved in heat-stress-associated skeletal muscle hypertrophy in vivo and in vitro. Therefore, it is strongly suggested that the application of heat stress to skeletal muscle might be a useful tool for an increase in muscle mass and force generation in elderly people.
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[Presentation] SOME ASPECTS OF NF-KAPPAB-RELATED SIGNALS IN HEAT STRESS-ASSOCIATED MUSCLE HYPERTROPHY IN RATS2009
Author(s)
Ohno, Y., Goto, K., Yamada, S., Sugiura, T., Ohira, Y., Yoshioka, T.
Organizer
第36回国際生理学会世界大会
Place of Presentation
国立京都国際会館
Year and Date
2009-07-29
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