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2009 Fiscal Year Final Research Report

Study on synergistic effect of flavonoids and other compounds on availability of flavonoids in vivo

Research Project

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Project/Area Number 19780092
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Food science
Research InstitutionTohoku University

Principal Investigator

NAKAGAWA Kiyotaka  Tohoku University, 大学院・農学研究科, 准教授 (80361145)

Project Period (FY) 2007 – 2009
Keywordsエピガロカテキンガレート / カフェイン / フラボノイド / 吸収代謝 / 抱合化 / 生理機能向上 / 茶カテキン / 高感度分析法
Research Abstract

We had previously developed a method of food flvonoids. By using the method, in this study, we investigated whether food constituents (e.g., caffeine) affects the bioavailability of flavonoids in vivo. As results, a higher concentration of flavonoid (i.e., catechin) was observed when catechin and caffeine were co-administered to humans. The result provides new insight into the synergistic effect of flavonoids and other compounds on availability of flavonoids in vivo.

  • Research Products

    (5 results)

All 2009 2008 2007

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Effect of co-administration of tea epigallocatechin-3-gallate (EGCG) and caffeine on absorption and metabolism of EGCG in human.2009

    • Author(s)
      K. Nakagawa, K. Nakayama, M. Nakamura, P. Sookwong, T. Tsuduki, H. Niino, F. Kimura, T. Miyazawa
    • Journal Title

      Biosci. Biotech. Bioch. 73

      Pages: 2014-2017

    • Peer Reviewed
  • [Journal Article] 栄養生理作用解明のための食品と生体成分の分析法開発.2009

    • Author(s)
      仲川清隆
    • Journal Title

      日本栄養・食糧学会誌 62

      Pages: 113-121

    • Peer Reviewed
  • [Presentation] 高速液体クロマトグラフ-質量分析装置による脂質分析と栄養・食糧研究への活用2009

    • Author(s)
      仲川清隆
    • Organizer
      4th JOCS-ILSI Japan Joint Symposium 2009
    • Place of Presentation
      東京
    • Year and Date
      2009-11-07
  • [Presentation] 生物産業創成を視野に入れた食品・生体成分の分析法開発2008

    • Author(s)
      仲川清隆
    • Organizer
      食品分析研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-10
  • [Presentation] カフェイン摂取によるラットとヒトのカテキン吸収動態の変化2007

    • Author(s)
      中村美穂, 仲川清隆, 新納仁, 角田隆巳, 宮澤陽夫
    • Organizer
      第61回栄養・食糧学会本大会
    • Place of Presentation
      京都
    • Year and Date
      2007-05-18

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Published: 2011-06-18   Modified: 2016-04-21  

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