2009 Fiscal Year Final Research Report
An approach to establish a method that allows efficient screening of beneficial probiotic strains for livestock.
| Project/Area Number |
19780198
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Kyoto Prefectural University (2008-2009)
Hokkaido University (2007) |
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Principal Investigator |
INOUE Ryo Kyoto Prefectural University, 大学院・生命環境科学研究科, 講師 (70443926)
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| Project Period (FY) |
2007 – 2009
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| Keywords | プロバイオティクス / 上皮細胞 / ブタ / インターロイキン12 |
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| Research Abstract |
Effect of probiotics was evaluated with consideration of "effect on intestinal epithelial cells" and "host specificity". This study showed most probiotic lactic acid bacteria (LAB) did not affect considerably on gene expression of intestinal epithelial cells under physical condition but not inflammatory status. Additionally no host specificity was found at least in in vitro co-culture system of splenocyte, mesenteric lymph node tissue with LAB. Thus, probiotic strains effective on pigs could be screened by using mouse cells.
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