2010 Fiscal Year Final Research Report
Research of the involvement of ICC in the movement of the ileocaecal junctional area
| Project/Area Number |
19790500
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Gastroenterology
|
|---|
| Research Institution | Tokyo Women's Medical University |
|---|
Principal Investigator |
KIKUTA Sachiko Tokyo Women's Medical University, 医学部, 助教 (10367089)
|
|---|
| Project Period (FY) |
2007 – 2010
|
| Keywords | カハールの介在細胞 / 消化管 / 回盲部 / 免疫組織化学 |
|---|
| Research Abstract |
The distribution and ultrastructure of the interstitial cells of Cajal (ICC) has been examined in the guinea-pig ileocaecal junction including the valve. In the ileocaecal junction, ICC showed a dense distribution in close association with the nerves. In addition, ICC were observed around the submucosal plexus (ICC-SP). ICC-SP shared ultrastructural criteria with ICC in the tunica muscularis and expressed the neurokinin 1 receptor(NK1-R). These observations appear to provide morphological evidence that ICC including ICC-SP play an important role in the movement of the junctional area.
|
-
-
-
-
-
-
-
-
[Remarks] 宮本(菊田)幸子,小室輝昌,モルモット回盲部におけるカハールの介在細胞の形態学的解析,日本平滑筋学会雑誌,12巻,pj-48,2008
-
[Remarks] 宮本(菊田)幸子,江崎太一,小室輝昌,モルモット回盲部粘膜下層におけるKit陽性細胞の分布と平滑筋の走行,解剖学雑誌,83 supplement, p156, 2008
-
[Remarks] 宮本(菊田)幸子,江崎太一,小室輝昌,モルモット回盲部におけるカハールの介在細胞の免疫組織化学的解析,解剖学雑誌,82 supplement, p80, 2007
