2009 Fiscal Year Final Research Report
Clinical and neuropathological studies of frontotemporal dementia
| Project/Area Number |
19790827
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Yokohama City University |
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Principal Investigator |
KATSUSE Omi Yokohama City University, 附属病院精神科, 助教 (40420674)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 前頭側頭型認知症 / 語義失語 / 神経病理 / TDP-43 |
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| Research Abstract |
Frontotemporal dementia (FTD) is clinically and neuropathologically heterogeneous disorder. We retrospectively investigated early symptoms of cases with FTD. The results revealed that apathy or semantic aphasia is common among initial symptoms of FTD. We also reported some cases with autoimmune disease mimicking FTD. Neuropathological study of FTD revealed that degeneration of thetemporal pole is most likely to participate in the pathomechanism of semantic aphasia.
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[Journal Article] Neuropathological investigation of regions responsible for semantic aphasia in frontotemporal lobar degeneration.2009
Author(s)
Yamamoto R, Iseki E, Higashi S, Murayama N, Minegishi M, Sato K, Hino H, Fujisawa K, Kosaka K, Togo T, Katsuse O, et al.
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Journal Title
Dement Geriatr Cogn Disord. 27
Pages: 214-223
Peer Reviewed
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[Presentation] レビー小体型認知症の病理診断基準の妥当性の検討2009
Author(s)
山本京子, 藤城弘樹, 井関栄三, 峰岸通子, 笠貫浩史, 東晋二, 日野博昭, 藤澤浩四朗, 小阪憲司, 都甲崇, 勝瀬大海, 他
Organizer
第50回日本神経病理学会
Place of Presentation
高松
Year and Date
20090600
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