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2009 Fiscal Year Final Research Report

Development of auto detect and analysis system for PET imaging on acute cerebrovascular diseases

Research Project

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Project/Area Number 19790861
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionUniversity of Fukui

Principal Investigator

KOBAYASHI Masato  University of Fukui, 保健学系, 助教 (30444235)

Research Collaborator OKAZAWA Hidehiko  福井大学, 高エネルギー医学研究センター, 教授 (50360813)
KIYONO Yasushi  福井大学, 高エネルギー医学研究センター, 准教授 (50305603)
MORI Tetsuya  福井大学, 高エネルギー医学研究センター, 助教 (40397287)
Project Period (FY) 2007 – 2009
Keywords核医学(PET) / 画像解析 / 画像診断技術 / 画像診断コンピュータ支援技術
Research Abstract

The purpose of this study is to develop auto detect and analysis system combining our noninvasive 15O-PET examination method using computer-aided diagnosis technology for patients with cerebrovascular disease. Auto analysis system was developed by location of regions of interest and calculation of left-to-right ratio using Matlab and Image J software in animal and clinical study. We also added auto detection system of fissure of Sylvius and stroke areas as auto analysis system using Image J.

  • Research Products

    (15 results)

All 2010 2009 2008 2007 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (9 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] 18F-FDGを用いた脳PET検査の健常者データベースにおけるTransmission撮像および減弱補正法の影響2010

    • Author(s)
      小林正和, (他9名)
    • Journal Title

      日本放射線技術学会雑誌 20

      Pages: 42-48

    • Peer Reviewed
  • [Journal Article] Vasodilatory effect of adenosine triphosphate does not change cerebral blood flow: a PET study with 15O-water2009

    • Author(s)
      Hussain, R., Tsuchida, T., Kudo, T,., Kobayashi, M., (他4名)
    • Journal Title

      Annals of Nuclear Medicine 23

      Pages: 717-723

    • Peer Reviewed
  • [Journal Article] Validation of the calculation of the clearance rate constant (kmono) of [11C]acetate using parametric kmono image for myocardial oxidative metabolism2009

    • Author(s)
      Hussain, R., Kudo, T., Tsujikawa, T., Kobayashi, M., (他2名)
    • Journal Title

      Nuclear Medicine and Biology 36

      Pages: 877-882

    • Peer Reviewed
  • [Journal Article] Shorter examination method for the diagnosis of misery perfusion using count-based OEF elevation in 15O-gas PET2008

    • Author(s)
      Kobayashi, M., (他6名)
    • Journal Title

      Journal of Nuclear Medicine 49

      Pages: 242-246

    • Peer Reviewed
  • [Journal Article] Clinical implication and prognosis of normal baseline cerebral blood flow with impaired vascular reserve in patients with major cerebral artery occlusive disease

    • Author(s)
      Isozaki, M., Arai, Y., Kudo, T., Kiyono, Y., Kobayashi, M., (他3名)
    • Journal Title

      Annals of Nuclear Medicine (in press)

    • Peer Reviewed
  • [Presentation] Measurement of cerebral oxygen metabolism and oxygen metabolism of rats using injectable O-15 oxygen and steady-state method combining bolus and increscent injection2010

    • Author(s)
      Kobayashi, M.
    • Organizer
      International Conference on Brain Function and Development
    • Place of Presentation
      Fujita Hotel, (Fukui)
    • Year and Date
      20100125-20100126
  • [Presentation] Development of steadystate method combining bolus and increscent injection with a multiprogramming syringe pump2009

    • Author(s)
      Kobayashi, M.
    • Organizer
      The 24rd International Symposium on Cerebral Blood Flow and Metabolism & the 9th International Conference on Quantification of Brain Function with PET (Brain 09&Brain PET 09)
    • Place of Presentation
      Conference venue (USA)
    • Year and Date
      20090629-20090703
  • [Presentation] Measurement of cerebral oxygen metabolism of rats using injectable O-15 oxygen and steady-state method2009

    • Author(s)
      Kobayashi, M.
    • Organizer
      The 56th Annual Meeting of the Society of Nuclear Medicine
    • Place of Presentation
      Metro Toronto Convention Centre (Canada)
    • Year and Date
      20090613-20090617
  • [Presentation] [O-15]酸素ガス標識人工赤血球の定常投与法を用いた正常ラットの脳循環代謝測定2009

    • Author(s)
      小林正和
    • Organizer
      日本分子イメージング学会第4回総会・学術集会
    • Place of Presentation
      学術総合センター(東京都)
    • Year and Date
      20090514-20090515
  • [Presentation] 定常投与法による[15O]標識人工赤血球の脳循環代謝測定2009

    • Author(s)
      小林正和
    • Organizer
      第49回日本核医学会学術総会
    • Place of Presentation
      旭川グランドホテル(北海道)
    • Year and Date
      2009-10-02
  • [Presentation] 簡便なPET定量検査を目指した薬剤持続投与システムの確立2009

    • Author(s)
      小林正和
    • Organizer
      日本放射線技術学会第64回総会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-04-05
  • [Presentation] 新規小動物PET装置における15O標識水を用いた脳循環代謝測定の検討2008

    • Author(s)
      小林正和
    • Organizer
      第48回日本核医学会学術総会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      20081024-20081026
  • [Presentation] 新規小動物PET装置を利用した正常ラットの脳血流量測定2008

    • Author(s)
      小林正和
    • Organizer
      日本分子イメージング学会第3回総会・学術集会
    • Place of Presentation
      大宮ソニックシティ(埼玉県)
    • Year and Date
      20080522-20080523
  • [Presentation] 無採血脳PET検査法を用いた貧困灌流領域診断における短時間撮像法の検討2007

    • Author(s)
      小林正和
    • Organizer
      第47回日本核医学会学術総会
    • Place of Presentation
      仙台国際センター(宮城県)
    • Year and Date
      20071104-20071106
  • [Patent(Industrial Property Rights)] PET薬剤送出装置およびその作動方法2008

    • Inventor(s)
      小林正和, 岡沢秀彦
    • Industrial Property Rights Holder
      福井大学
    • Industrial Property Number
      特許・特公2010-017417
    • Filing Date
      2008-07-11

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Published: 2011-06-18   Modified: 2016-04-21  

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