2009 Fiscal Year Final Research Report
Improving accuracy of Iodine-125 permanent implant brachytherapy for prostate cancer based on real time in vivo dosimetry
| Project/Area Number |
19790909
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Osaka University (2008-2009)
Japanese Foundation For Cancer Research (2007) |
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Principal Investigator |
TAKAHASHI Yutaka Osaka University, 大学院・医学系研究科, 特任助教(常勤) (40353461)
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| Project Period (FY) |
2007 – 2009
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| Keywords | I125永久挿入治療 / 前立腺 / 生体内線量測定 / 高精度化 |
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| Research Abstract |
Iodine-125 permanent implant brachytherapy has been widely practiced treatment for localized prostate cancer. The purpose of this study is to establish the real time in vivo dosimetry system in this therapy using MOSFET 5-linear array. We evaluated the various physical characteristics and the overall dosimetric accuracy which reproduced clinical setting in the original phantom study. The result of phantom study showed that in vivo dosimetry in permanent implant brachytherapy can be performed within 15%. These results suggest further improvement of dosimetric accuracy.
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