2009 Fiscal Year Final Research Report
Adipsin, a new candidate factor in the process of spontaneous abortion, on the effects of complement system and lipid metabolism
| Project/Area Number |
19791176
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Osaka Prefecture University |
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Principal Investigator |
KUSAKABE Takeshi Osaka Prefecture University, 生命環境科学研究科, 助教 (20319536)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 生殖医学 / 妊娠生理学 |
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| Research Abstract |
Adipsin, a complemental activator, was detected prominently in the labyrinthine region of abortion placentas. But the complement component 3 and the alternative complement pathway was not markedly activated. Since Crry, an inhibitor for complement acting in the downstream of adipsin, increased, it was suggested that adipsin does not have a strong effect to activate complement system in the abortion placenta. Adipsin may have an influence in the lipid metabolism on the reproductive physiology.
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