2009 Fiscal Year Final Research Report
Ion transport system in the endolymphatic sac
Project/Area Number |
19791208
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Otorhinolaryngology
|
Research Institution | Kagawa University |
Principal Investigator |
MIYASHITA Takenori Kagawa University, 医学部, 助教 (60363214)
|
Project Period (FY) |
2007 – 2009
|
Keywords | 内耳 / 内リンパ嚢 / イオン輸送 / メニエール病 / イオンチャネル / Na+ / K+-ATPase / イオンイメージング / パッチクランプ |
Research Abstract |
The endolymphatic sac is believed to absorb the endolymph. This study focused on the ion transport control system in the endolymphatic sac. FXYD6 is a control factor of Na pump, and Na pump in the endolymphatic sac may produce Na+ driving force. We confirmed FXYD6 mRNA and protein expression in the endolymphatic sac by RT-PCR and immunohistochemistry. This results suggested that FXYD6 may control the ion transport in the endolymphatic sac.
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Research Products
(31 results)