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2008 Fiscal Year Final Research Report

Investigation into the role of TNF-alpha in diabetic retinopathy

Research Project

  • PDF
Project/Area Number 19791279
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Ophthalmology
Research InstitutionNagoya City University

Principal Investigator

MATSUBARA Akihisa  Nagoya City University, 大学院・医学研究科, 助教 (80336685)

Project Period (FY) 2007 – 2008
Keywords眼科学
Research Abstract

TNF-alpha産生阻害薬は糖尿病ラット網膜の白血球集積を抑制した。TNF-alpha産生阻害薬は糖尿病網膜症における白血球-血管内皮間の粘着能亢進を改善することが示唆された。

  • Research Products

    (5 results)

All 2009 2008 2007

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Pitavastatin attenuatesleukocyte-endothelial in teractions induced by ischemia-reperfusion injury in the rat retina.2009

    • Author(s)
      Miyaki K, Matsubara A, Nishiwaki A, Tomida K, Morita H, Yoshida M, Ogura Y.
    • Journal Title

      Curr Eye Res. 34(1)

      Pages: 10-17

    • Peer Reviewed
  • [Journal Article] Effect of posterior sub-tenon administration of triamcinolone acetonide on leukocyte dynamics in rat retinal microcirculation after panretinal photocoagulation.2008

    • Author(s)
      Mizuno D, Matsubara A, Ogura Y.
    • Journal Title

      Invest Ophthalmol Vis Sci. 49

      Pages: 2127-2133

    • Peer Reviewed
  • [Presentation] Aldose reductase inhibitor attenuates leukocyte-endothelial interaction in experimental diabetic retina in vivo.2008

    • Author(s)
      Hattori T, Matsubara A, Taniguchi K, Ogura Y
    • Organizer
      Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
    • Place of Presentation
      フォートローダーデール、米国
    • Year and Date
      20080427-0501
  • [Presentation] 糖尿病ラットにおける網膜白血球集積に対するアルドース還元酵素阻害薬の抑制効果2008

    • Author(s)
      服部知明、松原明久、谷口香織、小椋祐一郎
    • Organizer
      第112回日本眼科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      20080417-20
  • [Presentation] 糖尿病ラットにおける網膜白血球集積に対する腫瘍壊死因子(TNF-α)阻害薬の抑制効果2007

    • Author(s)
      服部知明、松原明久、小椋祐一郎
    • Organizer
      第111回日本眼科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      20070419-22

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Published: 2010-06-10   Modified: 2016-04-21  

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