2009 Fiscal Year Final Research Report
The elucidation of the mechanisms of dexamethasone-regulated osteoblast differentiation
| Project/Area Number |
19791351
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
MIKAMI Yoshikazu Nihon University, 歯学部, 助教 (80434075)
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| Project Period (FY) |
2007 – 2009
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| Keywords | デキサメサゾン / 骨芽細胞 |
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| Research Abstract |
In this study, we investigated the mechanisms by which dexamethasone (Dex) affects osteoblast differentiation. This study demonstrated that Dex regulated osteoblast differentiation on the cell-differentiation stage dependent manner, and that MAP kinase and Jak-STAT signaling pathway were involved in the mechanisms for the Dex-regulated osteoblast differentiation.
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