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2009 Fiscal Year Final Research Report

The influence that recovery of a chewing function by prosthetic treatment gives to higher brain function.

Research Project

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Project/Area Number 19791456
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field 補綴理工系歯学
Research InstitutionIwate Medical University

Principal Investigator

KOBAYASHI Takuya  Iwate Medical University, 歯学部, 助教 (50382635)

Project Period (FY) 2007 – 2009
Keywords有床義歯学
Research Abstract

In recent years, mastication has been suggested to increase neuronal activities in various regions of the human brain. However, little is known about influence of tooth loss on higher brain function in human. In this study, we used fMRI to assess the effect of aging on brain regional activity associated with chewing in dentulous persons, edentulous persons and denture wearing persons.
Three groups of neurologically healthy subjects were included in this study:a dentulous group, edentulous group, denture wearer group (A subject of this group is the same as edentulous group. ). The task paradigm was the random chewing of wax cube. The wax cubes essentially was without the odor and taste components.
In agreement with a previous finding, in all groups, chewing was associated with significant increases in the BOLD signal in various regions of the brain. In addition, in dentulous group and denture wearer group, BOLD signals were increased in the basal ganglia and cerebellum. In edentulous group, BOLD signals were not increased in the basal ganglia and cerebellum.
The activity pattern of the brain may change by the loss of the tooth and denture wearing.

  • Research Products

    (2 results)

All 2009

All Presentation (2 results)

  • [Presentation] ヒトにおける歯の喪失が高次脳機能に及ぼす影響.2009

    • Author(s)
      鳥谷悠, 小林琢也, 鈴木哲也, 松村豊, 久喜薫子, 野村太郎, 横瀬隆夫, 澤田愛, 佐々木健, 箱崎守男
    • Organizer
      第118回日本補綴歯科学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      20090600
  • [Presentation] 補綴治療による咀嚼機能の回復が高次脳機能に及ぼす影響3T-fMRIを用いた脳賦活部位の検討.2009

    • Author(s)
      鳥谷悠, 小林琢也, 鈴木哲也, 箱崎守男
    • Organizer
      第20回日本老年歯科医学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      20090600

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Published: 2011-06-18   Modified: 2016-04-21  

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