2009 Fiscal Year Final Research Report
Basic research on analyzes influence of biological apatite crystal gives Osseointegration.
Project/Area Number |
19791462
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
補綴理工系歯学
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Research Institution | Nihon University |
Principal Investigator |
NAKADA Hiroshi Nihon University, 松戸歯学部, 講師 (10349970)
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Co-Investigator(Renkei-kenkyūsha) |
SAKAE Toshiro 日本大学, 松戸歯学部, 准教授 (20112948)
NUMATA Yasuko 日本大学, 松戸歯学部, 大学院生
LEGEROS Racquel Z. University College of Dentistry, Department of Biomaterials & Biomimetics, Professor
LEGEROS John P New York University College of Dentistry, Department of Biomaterials & Biomimetics, Professor
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Project Period (FY) |
2007 – 2009
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Keywords | 歯学 / 細胞・組織 / 骨 / 動物 / インプラント |
Research Abstract |
The purpose of this study was to investigate changes in bone quality associated with the mineralization of new bone forming around implants. This study investigated the quality and composition of new bone that formed around implants at 4 and 8 weeks post-implantation, compared to those of cortical bone. In new bone near cortical bone, PO_4^<3->, CO_3^<2->, and amide I distributions increased over time, and calcification progressed. In new bone more distant from cortical bone, PO_4^<3->, CO_3^<2->, and amide I distributions also increased over time, but to a lesser extent compared to that close to cortical bone. Our findings clearly showed changes in bone quality related to the degree of mineralization, based on sequential changes in chemical bonding and the distribution of elements and molecules comprising bone.
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[Journal Article] インプラント周囲に形成された新生骨をX-ray Photoelectron Spectroscopy分析により骨質評価を行った基礎的研究2008
Author(s)
中田浩史, 沼田靖子, 寒河江登志朗, 諏訪武利, 佐伯啓行, 谷本安浩, 加藤仁夫, 河相安彦, 金澤英作, 小林喜平, Racquel Z. LeGeros
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Journal Title
日大口腔科学 34(2)
Pages: 52-62
Peer Reviewed
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