2010 Fiscal Year Final Research Report
The relation between transmission from mothers to their infants and biofilm in the major pathogen of human dental caries
| Project/Area Number |
19791566
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MOTEGI Mizuho Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教 (60422474)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKAGI Yuzo 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (30124697)
SENPUKU Hidenobu 国立感染症研究所, 細菌第一部, 室長 (20250186)
YONEZAWA Hideo 杏林大学, 大学院・医学研究科, 助教 (60453528)
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| Project Period (FY) |
2007 – 2010
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| Keywords | Streptococcus mutans / う蝕 / バイオフィルム / 母子感染 / 細菌 |
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| Research Abstract |
Streptococcus mutans, the major pathogen responsible for dental caries in humans, is a biofilm-forming bacterium. In this study, SMU832 and 833 of S.mutans genes may be related to acquirement of S.mutans from rearers such as mother. Moreover, the genes may be associated with biofilm development.
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