2009 Fiscal Year Final Research Report
Periodontal regeneration following BMP-root conditioning and collagen scaffold implantation.
Project/Area Number |
19791606
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Periodontal dentistry
|
Research Institution | Hokkaido University |
Principal Investigator |
MIYAJI Hirofumi Hokkaido University, 北海道大学病院, 講師 (50372256)
|
Project Period (FY) |
2007 – 2009
|
Keywords | 歯周組織再生 / BMP-2 / コラーゲン / スキャフォールド |
Research Abstract |
We examined whether combined therapy of BMP-conditioning and implantation of a collagen scaffold stimulated periodontal regeneration. The collagen scaffold was composed of collagen hydrogel and type I collagen sponge. Application of collagen scaffold promoted bone augmentation and periodontal regeneration with high biocompatibility and tissue replacing ability. Root surface conditioning with BMP and implantation of collagen scaffold sufficiently enhanced periodontal regeneration and rarely induced ankylosis. The combined therapy is expected to be a suitable therapy for periodontal tissue engineering.
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Research Products
(15 results)