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2008 Fiscal Year Final Research Report

Dynamic Pathway Prediction by Signature Analysisusing Multiple Edge

Research Project

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Project/Area Number 19800009
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Bioinformatics/Life informatics
Research InstitutionThe University of Tokyo

Principal Investigator

OHTA Yoshihiro  The University of Tokyo, 先端科学技術研究センター, 特任研究員 (80436592)

Project Period (FY) 2007 – 2008
Keywordsマルチプルエッジ / シグネチャ解析
Research Abstract

生物系公開データベースと文献情報から時間的・空間的に関連の深いパスウェイを高精度に抽出する研究を行った。また、属性となる情報を取得し、関係の近いパスウェイをクラスタリングすることで、高精度で網羅性の高いシグネチャパスウェイ知識ベースの構築を可能とした。さらに、ここで構築された知識ベースを用いて、発現データを入力とし変動しているパスウェイを自動的に同定するための予測実験を行った。

  • Research Products

    (3 results)

All 2008 2007

All Presentation (3 results)

  • [Presentation] MultipleSnapshots Obtained Using Genomic TilingArrays Reveal the Dynamics ofTranscription in Human UmbilicalEndothelial Cells2008

    • Author(s)
      Tatsuhiko Kodama, Yoshihiro Ohta, MengXu, Takashi Minami1, Youichiro Wada, Shu-ichi Tsutsumi, Shumpei Ishikawa,Takao HamakuboHiroyuki Aburatani, PeterR Cook, and Sigeo Ihara
    • Place of Presentation
      SydneyAustralia
    • Year and Date
      20080601-05
  • [Presentation] Robustness of the proteininteraction network2007

    • Author(s)
      Nobuhiko Oshida, Jun-ichi Kitakami, Naoko S. Nishikawa, Yoshihiro Ohta, and Sigeo Ihara
    • Organizer
      The 7thinternational workshop on advancedgenomics
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      20071127-28
  • [Presentation] High-resolution targetedproteomics of endogenousnuclear receptorcomprex using high-quality immunomagneticbeads2007

    • Author(s)
      Kenji Daigo, Takeshi Kawamura, SatoshiKatayose, Yoshihiro Ohta, Toshiya Tanaka, Sigeo Ihara, Tatsuhiko Kodama, TakaoHamakubo
    • Organizer
      Cold Spring Harbor LaboratoryMechanisms of Eukaryotic Transcriptionmeeting
    • Place of Presentation
      cold Spring Harbor, NY.
    • Year and Date
      2007-08-31

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Published: 2010-06-10   Modified: 2016-04-21  

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