2023 Fiscal Year Final Research Report
Structural mechanics of cytoskeletons
| Project/Area Number |
19H03199
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 43040:Biophysics-related
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| Research Institution | Yokohama City University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
木村 暁 国立遺伝学研究所, 遺伝メカニズム研究系, 教授 (10365447)
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| Project Period (FY) |
2019-04-01 – 2023-03-31
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| Keywords | 生物物理学 / 細胞生物学 |
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| Outline of Final Research Achievements |
The purpose of this study was to experimentally determine the structural and mechanical properties of cytoskeletal structures in living cells. By constructing a new intracellular magnetic tweezers using a magnetic liquid, we succeeded in applying external force directly to microtubules and actin skeletons and observing the remaining structural changes using a confocal microscope.
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| Free Research Field |
細胞生物物理学
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| Academic Significance and Societal Importance of the Research Achievements |
本研究は細胞骨格に直接力を加えることでその構造力学的性質を特徴付けた。これはより広い文脈では、細胞内構造の物性を直接測定した初めての研究の内の一つであり、細胞生物物理学分野において一定の学術的意義を持つものである。
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