Multi-modal neurorehabilitation for stroke patients with severe hemiplegia

2023 Fiscal Year Final Research Report

• Project/Area Number: 19H03985
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Review Section: Basic Section 59010:Rehabilitation science-related
• Research Institution: Meiji University
• Principal Investigator: Ono Yumie 明治大学, 理工学部, 専任教授 (10360207)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: ニューロフィードバック / BMI / 脳卒中 / 多感覚 / 適応型リハビリテーション

Outline of Final Research Achievements

A neurorehabilitation system was developed for stroke patients. Training to increase resting μ-wave activity significantly improved μ-wave band power and motor-related cortical response, demonstrating its effectiveness as training to alleviate spasticity. Rehabilitation using the proposed method showed a better outcome in the recovery of motor function in stroke patients compared to the conventional method. After training, patients showed a greater increase in EEG connectivity within the affected hemisphere during paretic hand movement, along with the greater the functional recovery. Based on these findings, we developed a stand-alone application "Rehavision", a system to support patients' independent training by real-time display of cortical and muscle activities of the user.

Free Research Field

生体医工学

Academic Significance and Societal Importance of the Research Achievements

脳卒中は超高齢化社会を迎えた我が国において重要な健康課題であり、特に手指の運動機能回復は患者の生活の質を大きく左右する。本研究は、新しいニューロリハビリテーションシステムの開発とその臨床適用を通じて、重度の手指麻痺患者の機能回復を促すリハビリテーションの可能性を検討した。従来の手法では利き手交換しか選択肢のなかった重度麻痺患者（Brunnstrom stage II-III）にも効果的なリハビリテーションを提供できる可能性を示した本研究は、国内外のリハビリテーション医療において大きな意義を持つと考えられる。