2021 Fiscal Year Final Research Report
Construction of Theory and Design Principle of Molecular Computing Systems Realizing Functional Multiplicity by Control Signal Sequences
| Project/Area Number |
19H04204
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Review Section |
Basic Section 62010:Life, health and medical informatics-related
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| Research Institution | The University of Electro-Communications |
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Principal Investigator |
Kobayashi Satoshi 電気通信大学, 大学院情報理工学研究科, 教授 (50251707)
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| Co-Investigator(Kenkyū-buntansha) |
小宮 健 国立研究開発法人海洋研究開発機構, 超先鋭研究開発部門(超先鋭研究プログラム), 研究員 (20396790)
藤本 健造 北陸先端科学技術大学院大学, 先端科学技術研究科, 教授 (90293894)
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | 分子コンピュータ / 分子ロボティクス / 計算モデル |
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| Outline of Final Research Achievements |
In order to develop the foundation for designing molecular computers which can execute various computational functions according to sequences of external control signals, we devised novel computational models with unknown behaviors which can be controlled by external signals, novel DNA devices responsive to external signals, a new sequence design system for finding DNA sequences for temperature dependent DNA devices, and finally collected data and knowledge which are important when using two different DNA devices in a system. The theoretical and experimental research discussions enabled to find an important knowledge that, when we construct a system, we need to partition reactions into reversible and irreversible ones based on their computational functions. Furthermore, the development of the new photo-responsive device makes us distinguish a single base difference of input DNA sequences, which suggests an important improvement in the developed computational models.
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| Free Research Field |
計算機科学
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| Academic Significance and Societal Importance of the Research Achievements |
従来の DNA コンピュータは，各計算機能ごとに DNA 配列を設計して実装する必要があったが，本研究は，外部からの信号（光照射や温度変化）系列による制御により，さまざまな計算機能を実現できる新しい分子コンピュータを提案し，そのような分子コンピュータによって何ができるのかを明らかにするために必要となる計算理論を構築した．これまでは，DNA 配列に計算機能をプログラミングしていたが，本研究により，外部信号系列にプログラミングするという新しい分子コンピュータの可能性を開拓した．
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