Development of "super-bio-functions" by plasma-activated biological substances

2023 Fiscal Year Annual Research Report

• Project/Area Number: 19H05462
• Research Institution: Nagoya University
• Principal Investigator: 堀 勝 名古屋大学, 低温プラズマ科学研究センター, 特任教授 (80242824)
• Co-Investigator(Kenkyū-buntansha): 梶山 広明 名古屋大学, 医学系研究科, 教授 (00345886) ; 伊藤 昌文 名城大学, 理工学部, 教授 (10232472) ; 片岡 洋祐 国立研究開発法人理化学研究所, 生命機能科学研究センター, 客員主管研究員 (40291033) ; 白谷 正治 九州大学, システム情報科学研究院, 教授 (90206293) ; 豊國 伸哉 名古屋大学, 医学系研究科, 教授 (90252460) ; 榊原 均 名古屋大学, 生命農学研究科, 教授 (20242852)
• Project Period (FY): 2019-04-23 – 2024-03-31
• Keywords: プラズマ誘起活性物質 / プラズマ医療 / プラズマ農業

Outline of Annual Research Achievements

今年度は、分担研究者豊國、梶山らと共同で、プラズマ活性溶液のファーストインヒューマンとして、プラズマ活性乳酸リンゲル液（PAL）の特定臨床研究が名古屋大学附属病院で始められ、健常人に対する安全性が示された。また、分担研究者伊藤らと共同で、トリプトファンを含む培養液で培養された大腸菌に酸素ラジカルを直接照射することによる大腸菌の殺傷効果について、ESRによりトリプトファンラジカルが生成されることを明らかにし、NMRやLC-MS/MSを用いて、いくつかの酸素ラジカル照射によるトリプトファン反応生成物を同定し、メタボローム解析とその後のフォローアップ実験により、解糖系が阻害され、GAPDHの活性が抑制されるという細胞内分子機構を明らかにし、これらの成果をまとめた論文がEnvironmental Technology & Innovation誌に公表された。また、これまでに豊國らと共同で、中皮腫細胞において、PAL照射後早期にリソソームで一酸化窒素の合成が誘導され、最終的にペルオキシナイトライトがリソソームを傷害し、それに伴ってオートファジーからフェロトーシスへの転換が起こるメカニズムを明らかにしていたが、更にがん細胞の鉄代謝にもPAL曝露に伴う大きな変化を見いだし、これらの成果を論文としてまとめ、Free Radical Biology and Medicineに掲載された。分担研究者古閑、榊原らとプラズマ農業に関する研究も進め、古閑らはプラズマ種子科学に関する学術変革領域Aを立ち上げた。これまでの研究成果により、2023年6月2日に第76回中日文化賞を受賞し、2024年3月22日に第24回応用物理学会業績賞を受賞し、「ラジカル制御プラズマプロセスの先駆的研究」というタイトルで受賞講演を行った。

Research Progress Status

令和5年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和5年度が最終年度であるため、記入しない。

Research Products

• [Journal Article] Cancer-specific cytotoxicity of Ringer’s acetate solution irradiated by cold atmospheric pressure plasma (2023)
  • Author(s): Camelia Miron , Kenji Ishikawa, Satoshi Kashiwagura, Yuki Suda, Hiromasa Tanaka, Kae Nakamura, Hiroaki Kajiyama, Shinya Toyokuni, Masaaki Mizuno, Masaru Hori
  • Journal Title: Free Radical Research Volume: Volume 57, 2023 - Issue 2 Pages: 91-104
  • DOI: 10.1080/10715762.2023.2201390
  • Peer Reviewed / Open Access
• [Journal Article] Generation and measurement of low temperature plasma for cancer therapy: a historical review (2023)
  • Author(s): Kenji Ishikawa, Keigo Takeda, Shinji Yoshimura, Takashi Kondo, Hiromasa Tanaka, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, Masaaki Mizuno, and Masaru Hori
  • Journal Title: FREE RADICAL RESEARCH Volume: 2023, VOL. 57, NO. 3, Pages: 239-270
  • DOI: 10.1080/10715762.2023.2230351
  • Peer Reviewed / Open Access
• [Journal Article] Tetrachloroaurate (III)-induced oxidation increases nonthermal plasma-induced aldehydes (2023)
  • Author(s): Yasumasa Okazaki, Jun Yoshitake, Nanami Ito, Kanako Sasaki, Hiromasa Tanaka, Masaru Hori, Takahiro Shibata, Shinya Toyokuni
  • Journal Title: Advances in Redox Research Volume: Volume 9, December 2023, Pages: 100074
  • DOI: 10.1016/j.arres.2023.100074
  • Peer Reviewed / Open Access
• [Journal Article] Efficacy of periodic cold plasma treatment in a paddy to produce white-core grains in brewer's rice cultivar Yamadanishiki (2023)
  • Author(s): Hiroshi Hashizume, Hidemi Kitano, Hiroko Mizuno, Akiko Abe, Genki Yuasa, Satoe Tohno, Hiromasa Tanaka, Kenji Ishikawa, Shogo Matsumoto, Hitoshi Sakakibara, Yoji Hirosue, Masayoshi Maeshima, Masaaki Mizuno & Masaru Hori
  • Journal Title: Free Radical Research Volume: Volume 57, 2023 - Issue 3 Pages: 161-173
  • DOI: 10.1080/10715762.2023.2215914
  • Peer Reviewed / Open Access
• [Journal Article] New betulin imine derivatives with antioxidant and selective antitumor activity (2023)
  • Author(s): Manuela-Maria Iftime, Gabriela Liliana Ailiesei, Camelia Miron, Hiromasa Tanaka, Masaru Hori and Luminita Marin
  • Journal Title: New Journal of Chemistry Volume: Volume47, Issue35 Pages: 16551-16563
  • DOI: 10.1039/d3nj02738d
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The Possibility of Cancer Therapy with a Combination of Low Temperature Plasma and Hyperthermia (2023)
  • Author(s): TAKASHI KONDO, HIROSHI HASHIZUME, HIROMASA TANAKA, KENJI ISHIKAWA, JUN-ICHI SAITOH MASARU HORI
  • Journal Title: Thermal Medicine Volume: Volume 39 Issue 3 Pages: 21-30
  • DOI: 10.3191/thermalmed.39.21
  • Peer Reviewed / Open Access
• [Journal Article] Ferroptosis induced by plasma-activated Ringer's lactate solution prevents oral cancer progression (2023)
  • Author(s): Kotaro Sato, Ming Yang, Kae Nakamura, Hiromasa Tanaka, Masaru Hori, Miki Nishio, Akira Suzuki, Hideharu Hibi, Shinya Toyokuni
  • Journal Title: Oral Diseases Volume: Early View 12/5 Pages: 1-13
  • DOI: 10.1111/odi.14827
  • Peer Reviewed / Open Access
• [Journal Article] Oxygen radical irradiation transforms an organic fertilizer l-tryptophan into an environment and human-friendly bactericide (2023)
  • Author(s): Naoyuki Iwata , Kenji Ishikawa, Yasuhiro Nishikawa, Hiroyuki Kato, Motoyuki Shimizu, Masashi Kato, Hiromasa Tanaka, Masafumi Ito, Masaru Hori
  • Journal Title: Environmental Technology &Innovation Volume: Volume 33, Pages: 103496
  • DOI: 10.1016/j.eti.2023.103496
  • Peer Reviewed / Open Access
• [Presentation] Increase of yield and quality with cold plasma treatment during crop cultivation (2024)
  • Author(s): Hiroshi Hashizume, Hidemi Kitano, Shogo Matsumoto, Hiroko Mizuno, Akiko Abe, Kaoru Sanda, Genki Yuasa, Satoe Tohno, Mikiko Kojima, Yumiko Takebayashi, Hiromasa Tanaka, Kenji Ishikawa, Masafumi Ito, Naofumi Kamoshita, yoji Hirosue, Hitoshi Sakakibara, Masayoshi Maeshima, Masaaki Mizuno, and Masaru Hori
  • Organizer: 5th International Symposium of the Vacuum Societyof the Philippines (ISVSP 2024)
  • Int'l Joint Research / Invited
• [Presentation] Sustainable Innovations of the Low-Temperature Plasma-Agriculture (2024)
  • Author(s): Kenji Ishikawa, Hiroshi Hashizume, Hidemi Kitano, Hiromasa Tanaka, and Masaru Hori
  • Organizer: Next-generation Circular Bio Economy Celebration of the 70th Anniversary of Friendship between Japan and Cambodia
  • Int'l Joint Research
• [Presentation] Radical enhanced growth of GaN on Si with a buffer growth of GaN at low temperature of 600°C (2024)
  • Author(s): Swathy Jayaprasad, Arun Kumar Dhasiyan, Naohiro Shimizu, Osamu Oda, Kenji Ishikawa, Hiromasa Tanaka and Masaru Hori
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Plasma irradiation induces changes in the survival rate and composition of zebrafish (2024)
  • Author(s): Yuya Kurebayashi, Kenji Ishikawa, Hiromasa Tanaka, Shinichi Akiyama, Hiroshi Hashizume, Camelia Miron and Masaru Hori
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Control of hMSC differentiation in culturing on carbon nanowalls (2024)
  • Author(s): Yuki Kojima, Hiroki Kondo, Kenji Ishikawa, Masaru Hori, Hiromasa Tanaka
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Mechanisms of selective killing of MCF7 against MCF10A by plasma-activated Ringer’s lactate solution (2024)
  • Author(s): Ayako Tanaka, Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Camelia Miron, Hiroshi Hashizume, Yasumasa Okazaki, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, and Masaru Hori
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Investigation of Autophagy Inducer on Cancer Cell Treated by PAL (2024)
  • Author(s): Taishi Yamakawa, Kae Nakamura, Masaaki Mizuno, Shinya Toyokuni, Hiroaki Kajiyama, Masaru Hori, Kenji Ishikawa and Hiromasa Tanaka
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Low-Temperature Plasma- and Radiation-Induced Free Radicals of Solid-State Amino Acids (2024)
  • Author(s): Takashi Kondo, Jun Kumagai, Ryoichi Hirayama Hiroshi Hashizume, Hiromasa Tanaka, Kenji Ishikawa and Masaru Hori
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Plasma-Activated Ringer’sLactate Solution Prevents OralCancer Progression throughCollagenousMatrixFormation (2024)
  • Author(s): Kotaro Sato, Ming Yang, Kae Nakamura, Hiromasa Tanaka, Masaru Hori, Hideharu Hibi and ShinyaToyokuni
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] Selective Killing Effects on Human Breast Cancer Cells by Plasma-Treated L-Arginine Solution (2024)
  • Author(s): Liyin Du, Carmelia Miron, Kenji Ishikawa, Masaru Hori, Masaaki Mizuno, Shinya Toyokuni, Hiroaki Kajiyama and Hiromasa Tanaka
  • Organizer: ISPlasma2024/IC-PLANTS2024/APSPT-13
  • Int'l Joint Research
• [Presentation] HAuCl4が誘導する脂質過酸化はNTP照射と相乗的に増大し、アスコルビン酸によって抑制される (2024)
  • Author(s): 清水美里、岡崎泰昌、吉武淳、伊藤七海、田中宏昌、堀勝、柴田貴宏、豊国伸哉
  • Organizer: 第113回日本病理学会総会
• [Presentation] 低温プラズマ誘発細胞死の温熱による増強-直接照射から照射溶液へ (2024)
  • Author(s): 近藤 隆、村谷珠輝、古澤之裕、齋藤淳一、橋爪博司、田中宏昌、石川健司 、堀 勝
  • Organizer: 第24回 菅原・大西記念 癌治療増感シンポジウム
• [Presentation] 大気圧酸化窒素ラジカル源への水蒸気添加効果 (2024)
  • Author(s): 杉江 恭輔, 山本 航大, 呉 準席, 田中 宏昌, 堀 勝, 伊藤 昌文
  • Organizer: 第７６回応用物理学会春季学術講演会
• [Presentation] がん細胞におけるPAL内オートファジー誘導物質に関する評価 (2024)
  • Author(s): 山川 太嗣, 中村 香江, 梶山 広明, 豊國 伸哉, 水野 正明, 石川 健治, 堀 勝, 田中 宏昌
  • Organizer: 第７７回応用物理学会春季学術講演会
• [Presentation] プラズマ活性化溶液によるイチゴ果実成熟促進 (2024)
  • Author(s): 橋爪 博司, 松本 省吾, 坪田 憲紀, 三田 薫, 阿部 明子, 水野 寛子, 湯浅 元気, 東野 里江, 田中 宏昌, 石川 健治, 伊藤 昌史, 北野 英己, 鴨下 直史, 広末 庸治, 榊原 均, 前島 正義, 水野 正明, 堀 勝
  • Organizer: 第８０回応用物理学会春季学術講演会
• [Presentation] High Performances of Plasma-activated Lactated Ringer’s Solution for Medical Treatment (2023)
  • Author(s): Masaru Hori, Hiromasa Tanaka, Camelia Miron, Kenji Ishikawa, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama and Masaaki Mizuno
  • Organizer: The 14th EU-Japan Joint Symposium on Plasma Processing ( JSPP-14)
  • Int'l Joint Research / Invited
• [Presentation] Efficacy of cold plasma for strawberry cultivation on fruit ripening process (2023)
  • Author(s): Hiroshi Hashizume, Shogo Matsumoto, Hitoshi Sakakibara, Kaoru Sanda, Akiko Abe, Hiroko Mizuno, Kenki Tsubota, Mikiko Kojima, Yumiko Takebayashi, Genki Yuasa, Satoe Tohno, Hiromasa Tanaka, Kenji Ishikawa, Masafumi Ito, Hidemi Kitano, Takayuki Okuma, Yuji Hirosue, Masayoshi Maeshima, Masaaki Mizuno, and Masaru Hori
  • Organizer: 25th International Symposium on Plasma Chemistry (ISPC25)
  • Int'l Joint Research
• [Presentation] Activation of strawberry fruit ripening with cold plasma treatment during cultivation (2023)
  • Author(s): Hiroshi Hashizume, Shogo Matsumoto, Kaoru Sanda, Hiroko Mizuno, Akiko Abe, Genki Yuasa, Satoe Tohno, Mikiko Kojima, Yumiko Takebayashi, Hiromasa Tanaka, Kenji Ishikawa, Masafumi Ito, Hidemi Kitano, Hitoshi Sakakibara,Takayuki Okuma, Yoji Hirosue, Masayoshi Maeshima, Masaaki Mizuno, and Masaru Hori
  • Organizer: 4TH INTERNATIONAL WORKSHOP ON PLASMA AGRICULTURE (IWOPA4)
  • Int'l Joint Research
• [Presentation] Plasma-bio application using plasma-activated solutions (2023)
  • Author(s): Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Hiroaki Kajiyama, Shinya Toyokuni, Masaru Hori
  • Organizer: 65th KVS Suumer Annual Conference & IFFM 2023
  • Int'l Joint Research / Invited
• [Presentation] Plasma-activated solutions for bio-medical application (2023)
  • Author(s): Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Hiroaki Kajiyama, Shinya Toyokuni, Masaru Hori
  • Organizer: 3rd Asia pacific conference on plasma and terahertz science(APCOPTS)
  • Int'l Joint Research / Invited
• [Presentation] Physicochemical investigation of plasma treated polymer solutions for cancer treatment (2023)
  • Author(s): Camelia Miron, Hiromasa Tanaka, Taishi Yamakawa, Du Lyin, Hiroki Kondo, Hiroshi Hashizume, Takashi Kondo, Kenji Ishikawa, Shinya Toyokuni, Masaaki Mizuno, and Masaru Hori
  • Organizer: MACRO 2023 Symposium at ICMPP, IASI
  • Int'l Joint Research
• [Presentation] Cold Atmospheric Pressure Plasma-Activated Liquids for Cancer Treatment (2023)
  • Author(s): Camelia Miron, Hiromasa Tanaka, Nikolay Britun, Kenji Ishikawa, Du Liyin, Taishi Yamakawa, Yuya Kurebayashi, Takashi Kondo, Hiroki Kondo, Hiroaki Kajiyama, Shinya Toyokuni, Masaaki Mizuno, Masaru Hori
  • Organizer: The 11th IEEE International Conference on E-Health and Bioengineering(EHB2023)
  • Int'l Joint Research / Invited
• [Presentation] Biomedical applications of plasma-activated solutions (2023)
  • Author(s): Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Camelia Miron, Yasumasa Okazaki, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, Masaru Hori
  • Organizer: The 76th Annual Gaseous Electronics Conference (GEC76)
  • Int'l Joint Research / Invited
• [Presentation] Chemically Active Compounds Formed in Low-temperature Plasma Treated Liquids for Cancer Treatment (2023)
  • Author(s): Camelia Miron, Hiromasa Tanaka, Taishi Yamakawa, Du Lyin, Hiroki Kondo, Hiroshi Hashizume, Takashi Kondo, Kenji Ishikawa, Shinya Toyokuni, Masaaki Mizuno, and Masaru Hori
  • Organizer: Global Plasma Forum in Aomori
  • Int'l Joint Research
• [Presentation] Selective Cytotoxicity of Plasma-Treated L-Arginine Solution on Human Breast Cancer Cells (2023)
  • Author(s): Liyin Du, Camelia Miron, Takashi Kondo, Hiromasa Tanaka, Kenji Ishikawa, Masaaki Mizuno, Shinya Toyokuni, Hiroaki Kajiyama, and Masaru Hori
  • Organizer: 13th Asian-European International Conference on Plasma Surface Engineering (AEPSE 2023)
  • Int'l Joint Research
• [Presentation] Low-temperature plasma as a ferroptosis inducer in cancer cells (2023)
  • Author(s): Shinya Toyokuni, Hao Zheng, Yasumasa Okazaki, Kae Nakamura, Hiroaki Kajiyama, Hiromasa Tanaka, Keiji Ishikawa and Masaru Hori
  • Organizer: Global Plasma Forum in Aomori
  • Int'l Joint Research / Invited
• [Presentation] Ferroptosis induced by plasma-activated Ringer's lactate solution prevents oral cancer progression (2023)
  • Author(s): Kotaro Sato, Ming Yang, KaeNakamura, Hiromasa Tanaka, Masaru Hori, Miki Nishio, Akira Suzuki, Hideharu Hibi, Shinya Toyokuni
  • Organizer: Global Plasma Forum in Aomori
  • Int'l Joint Research
• [Presentation] Plasma-activated solutions invigorate anti-tumor immune response in the intraperitoneal environments of ovarian cancer (2023)
  • Author(s): Kae Nakamura, Nobuhisa Yoshikawa, Hiromasa Tanaka, Kenji Ishikawa, Masaaki Mizuno, Shinya Toyokuni, Masaru Hori and Hiroaki Kajiyama
  • Organizer: Global Plasma Forum in Aomori
  • Int'l Joint Research
• [Presentation] Mechanisms of selective killing of cancer cells against normal cells by plasma-activated Ringer’s lactate solution. (2023)
  • Author(s): Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Camelia Miron, Hiroshi Hashizume, Yasumasa Okazaki, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, and Masaru Hori
  • Organizer: 13th Asian-European International Conference on Plasma Surface Engineering (AEPSE 2023)
  • Int'l Joint Research
• [Presentation] Evaluation of Autophagy-Inducing Substances in PAL (2023)
  • Author(s): Taishi Yamakawa,Kae Nakamura, Masaaki Mizuno, Shinya Toyokuni, Hiroaki Kajiyama, Masaru Hori, Kenji Ishikawa and Hiromasa Tanaka
  • Organizer: 13th Asian-European International Conference on Plasma Surface Engineering (AEPSE 2023)
  • Int'l Joint Research
• [Presentation] Cellular Response to Electrical Stimulation on Carbon Nanowalls Coated with Silicon Carbide (2023)
  • Author(s): Koki Ono, Hiroki Kondo, Kenji Ishikawa, Wakana Takeuchi, Kenichi Uehara, Shigeo Yasuhara, Hiromasa Tanaka and Masaru Hori
  • Organizer: 13th Asian-European International Conference on Plasma Surface Engineering (AEPSE 2023)
  • Int'l Joint Research
• [Presentation] 低温大気圧プラズマ、放射線およびH2O2-UVによるアミノ酸溶液におけるフリーラジカル生成 (2023)
  • Author(s): 近藤 隆、熊谷 純、平山亮一、橋爪 博司、田中 宏昌、石川 健治、堀 勝
  • Organizer: 日本放射線影響学会
• [Presentation] 大気圧プラズマ誘発細胞死の温熱による増強 (2023)
  • Author(s): 近藤 隆, 村谷珠輝、古澤之裕、斉藤淳一、橋爪博司、田中宏昌、石川健司、堀 勝
  • Organizer: 日本ハイパーサーミア学会
• [Presentation] アミノ酸水溶液のプラズマ化学および放射線化学－スピン捕捉法による検討 (2023)
  • Author(s): 近藤 隆，熊谷 純，橋爪 博司，田中 宏昌，石川 健治，堀 勝
  • Organizer: 第６６回放射線化学討論会
• [Presentation] 低温プラズマのバイオ応用?農作物栽培におけるプラズマの効果? (2023)
  • Author(s): 橋爪博司，北野英己，松本省吾，阿部明子，水野寛子，三田 薫，湯浅元気，東野里江，田中宏昌，石川健治，伊藤昌文，榊原 均，広末庸治，鴨下直史，前島正義，水野正明，堀 勝
  • Organizer: 第６６回放射線化学討論会
  • Invited
• [Presentation] 低温プラズマのバイオ応用～プラズマ照射効果～ (2023)
  • Author(s): 石川 健治，近藤 隆，田中 宏昌，豊國 伸哉，中村 香江，梶山 広明，水野 正明，堀 勝
  • Organizer: 第６６回放射線化学討論会
  • Invited
• [Presentation] プラズマ照射が引き起こすゼブラフィッシュの生残率と含有成分に対する影響 (2023)
  • Author(s): 紅林 佑弥,石川 健治,橋爪 博司,田中 宏昌,秋山 真一,堀 勝
  • Organizer: 第33回日本MRS年次大会
• [Presentation] プラズマ活性乳酸リンゲル液によるマクロファージのM1極性誘導 (2023)
  • Author(s): 出野 雄大, 田中 宏昌, 石川 健治, 橋爪 博司, 中村 香江, 豊國 伸哉, 水野 正明, 梶山 広明,堀 勝
  • Organizer: 第33回日本MRS年次大会
• [Presentation] 高密度大気圧プラズマ源によって生成されたイオン種と中性活性種の照射距離依存性 (2023)
  • Author(s): 杉江 恭輔、呉 準席、田中 宏昌、堀 勝、伊藤 昌文
  • Organizer: 第84回応用物理学会秋季学術講演会
• [Presentation] カーボンナノウォール上でのヒト間葉系幹細胞の多分化能制御に関する研究 (2023)
  • Author(s): 小島 悠暉、近藤 博基、石川 健治、堀 勝、田中 宏昌
  • Organizer: 第84回応用物理学会秋季学術講演会
• [Presentation] SiC被覆カーボンナノウォール足場上での電気刺激重畳培養における骨芽細胞の挙動 (2023)
  • Author(s): 小野 浩毅、近藤 博基、石川 健治、竹内 和歌奈、上原 賢一、安原 重雄、堀 勝、田中 宏昌
  • Organizer: 第84回応用物理学会秋季学術講演会
• [Presentation] PAL内成分ががん細胞に誘発するオートファジーの評価 (2023)
  • Author(s): 山川 太嗣、中村 佳江、梶山 広明、豊國 伸哉、水野 正明、石川 健治、堀 勝、田中 宏昌
  • Organizer: 第84回応用物理学会秋季学術講演会
• [Presentation] プラズマ処理によるイチゴ果実中のアントシアニン合成活性化の解析 (2023)
  • Author(s): 橋爪 博司、松本 省吾、三田 薫、小嶋 美紀子、竹林 由美子、阿部 明子、水野 寛子、坪田 憲紀、湯浅 元気、東野 里江、田中 宏昌、石川 健治、伊藤 昌文、北野 英己、大熊 隆之、広末 庸治、榊原 均、前島 正義、水野 正明、堀 勝
  • Organizer: 第84回応用物理学会秋季学術講演会
• [Book] Advances in Digital Health and Medical Bioengineering (2024)
  • Author(s): C. Miron, H. Tanaka, N. Britun, H. Hashizume, K. Ishikawa, D. Liyin, T. Yamakawa, Y. Kurebayashi, K. Kondo, H. Kondo, H. Kajiyama, S. Toyokuni, M. Mizuno, M. Hori
  • Total Pages: 600
  • Publisher: Springer Nature
  • ISBN: 978-3-031-62522-0