2023 Fiscal Year Final Research Report
Bacterial Chemotaxis Reproduced by Collection of Self-Propelled Objects
| Project/Area Number |
19K03676
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 13010:Mathematical physics and fundamental theory of condensed matter physics-related
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| Research Institution | Meiji University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
小田切 健太 専修大学, ネットワーク情報学部, 准教授 (20552425)
池田 幸太 明治大学, 総合数理学部, 専任准教授 (50553369)
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| Project Period (FY) |
2019-04-01 – 2024-03-31
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| Keywords | 自己駆動粒子 / 環境応答性 / 走化性 / 確率微分方程式 / 界面化学 |
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| Outline of Final Research Achievements |
In this project, we focused on chemotaxis of self-propelled particles. It was known that a nonliving solid particles can show spontaneous motion on water surface, furthermore, run-and-tumble behavior could be reproduced with a chemical reaction where the reactant was in the water phase. "Run-and-tumble" is well known characteristic behavior of bacteria, which succeeds chemotaxis by tuning periods of run and tumble depending on the surrounding chemical conditions. Similarly, our nonliving self-propelled particles showed chemotaxis response to chemical concentration gradient. In addition, our observations were reproduced by a simple random walker model. We mathematically analyzed the model and got a profile of existing distribution mathematically. This result indicates that bacterial chemotaxis was well reproduced by nonliving matter and the fundamental mechanism was almost same. Therefore, our findings are probably applied to variety of situations and materials.
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| Free Research Field |
非線形科学
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| Academic Significance and Societal Importance of the Research Achievements |
自己駆動粒子の開発は近年様々な物質で行われ、種々の機能が実現されてきている。その中で、走化性をはじめとする環境応答性は最も重要な機能の一つである。これまでは、外部環境の優位な勾配に決定論的に応答する系が多く開発されてきたが、系が小さくなると、勾配の影響が小さくなるため、バクテリアで実現されているような確率的な応答が求められる。今回、我々が明らかにした実験系はバクテリアの走化性にみられる戦略をうまく再現しており、その実装可能性を示すことができた。今後、ドラッグデリバリーシステムのように、自発的な環境応答性が求められる場に対しての応用が期待される成果である。
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