Establishment of Induction Heating Theory for Magnetic Nanoparticles by Fusion of Theories in Different Fields and Development of Novel Nanoparticle Synthesis Process

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K05216
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 28030:Nanomaterials-related
• Research Institution: Osaka Metropolitan University (2022); Osaka Prefecture University (2019-2021)
• Principal Investigator: Iwasaki Tomohiro 大阪公立大学, 大学院工学研究科, 教授 (50295721)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 磁性ナノ粒子 / 誘導加熱 / 磁気ハイパーサーミア / フェライト

Outline of Final Research Achievements

For realizing magnetic hyperthermia treatment as a new cancer therapy, induction heating theory and synthesis of magnetic nanoparticles with suitable properties are required. To achieve this, the relationship between an anisotropy parameter, which is an index of the magnetic anisotropy, and an amount of induction heating was focused. Effects of the magnetic dipolar interaction of superparamagnetic nanoparticles on the induction heating was investigated theoretically and experimentally. As a result, an essential mechanism in the induction heating was revealed, which provided a guide for development of a new theory for hyperthermia treatment.

Free Research Field

化学工学

Academic Significance and Societal Importance of the Research Achievements

現在のがん治療法は、治療効果は大きいものの、治療時の患者への身体的・精神的負担が大きく、また、高額な治療費など、早急に改善すべき課題が残されている。新しいがん治療法の一つである温熱治療(磁気ハイパーサーミア)は、これらの問題の解決策の一つとして期待されている。本研究の成果は、磁気ハイパーサーミアの実現に向けて必要不可欠な誘導加熱の予測と治療に用いる発熱材料の合成に関する技術の進歩に寄与するものである。