Spot measurement of alanine radicals produced by irradiation and application of sugar radial to dosimeter

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K05343
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 31010:Nuclear engineering-related
• Research Institution: Tokyo Metropolitan Industrial Technology Research Institute
• Principal Investigator: Nakagawa Seiko 地方独立行政法人東京都立産業技術研究センター, 事業化支援本部技術開発支援部計測分析技術グループ, 主任研究員 (30462980)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: ESR / ラジカル / アラニン / 糖

Outline of Final Research Achievements

ESR spectral change of alanine radicals produced by soft X-ray irradiation was observed for the first time by spot measurement. The efficiency of the radical yield by the soft X-ray irradiation was much loser relative to that by gamma irradiation and the product formed by the radical recombination was observed. It means that the soft X-ray irradiation is a high-LET irradiation. The radicla yield efficiency decreased with decreasing the energy of soft X-ray.
The dose response and time dependence of radicals produced in fructose, mixed glucose, alpha-glucose, beta-glucose and sucrose were investigated in detail. It was found that beta-glucose is the best substance for the dosimeter.

Free Research Field

放射線化学

Academic Significance and Societal Importance of the Research Achievements

線量計として広く使用されているアラニンへの軟X線照射により、軟X線のエネルギー低下に伴い、高LET照射である事が判明した。これは、放射線照射の生物効果への軟X線の影響に関する示唆を与えるのみならず、軟X線リソグラフィーなど産業利用においても新たな知見を与える。
スクロースのラジカルの線量計への応用は、原子力施設の事故の際の線量評価などが期待されている。本研究で、βグルコースが、より線量応答性や安定性で優れている事が判明し、新たな線量計開発の可能性が開けた。