Synthesis of Novel HF-Base Complexes and Their Application to Fluorine Recycling System

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K05567
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 34030:Green sustainable chemistry and environmental chemistry-related
• Research Institution: Shibaura Institute of Technology
• Principal Investigator: Tajima Toshiki 芝浦工業大学, 工学部, 教授 (50361770)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: HF-塩基錯体 / 有機強塩基 / KF / 固体酸 / カチオン交換反応 / 電解フッ素化 / 求核的フッ素化

Outline of Final Research Achievements

We have successfully synthesized a variety of HF-base complexes (nucleophilic fluorinating agents) based on cation exchange reaction between KF and a solid-supported acid. Furthermore, the reactivity of the synthesized HF-base complexes was evaluated by using the ring-opening fluorination of aryl epoxide as a model reaction. As a result, it was clarified that the reactivity of the HF-base complexes changes greatly depending on the basicity and structure of the base used.

Free Research Field

有機電気化学

Academic Significance and Societal Importance of the Research Achievements

有機フッ素化合物は医薬品や農薬、機能性材料などにおいて幅広く利用されており、その需要は益々高まっている。これに対し、本研究成果は有機フッ素化合物を合成するためのフッ素化剤（HF-塩基錯体）の新たな合成法を提供するものであり、さらにHF-塩基錯体の反応性を学術的に明らかにした。また、HF-塩基錯体を固体塩基に応用することで、HFを含む廃液からのHFの回収の実現について、その可能性を示唆した。