Investigation of epigenetic mechanism underlying longevity in honeybee.

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K06077
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 39050:Insect science-related
• Research Institution: Toyama Prefectural University
• Principal Investigator: Kamakura Masaki 富山県立大学, 工学部, 講師 (60363876)
• Co-Investigator(Kenkyū-buntansha): 齋藤 裕 国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 主任研究員 (60721496)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: ミツバチ / 寿命 / 幼若ホルモン / 受容体

Outline of Final Research Achievements

We conducted RNA-seq anaysis in Queens and Workers. GO analysis revealed that decrease of gene expression in energy metabolism and increase of gene expression in beta-oxidation induce the extension of longevity in Queens. Furthermore, we identified genes of juvenile hormone receptors, Methoprene tolerant and Steroid receptor co-activator in honeybees.

Free Research Field

昆虫生理学

Academic Significance and Societal Importance of the Research Achievements

本研究の成果は、養蜂における女王蜂管理技術の向上に活用できる。また、ミツバチのMetの同定は今後の新たな農薬開発に応用できる。