Regulation of TE-derived non-coding RNAs in plant genomes

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K06619
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 43050:Genome biology-related
• Research Institution: Okinawa Institute of Science and Technology Graduate University
• Principal Investigator: Hidetoshi Saze 沖縄科学技術大学院大学, 植物エピジェネティクスユニット, 准教授 (70510006)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: エピジェネティクス / トランスポゾン / 植物ゲノム

Outline of Final Research Achievements

In plant genomes, many transposable elements (TEs) are accumulated in genic regions including intron and untranslated regions (UTR) of genes. In this study, we investigated cryptic promoters that are regulated by epigenetic modifications. In Arabidopsis thaliana, we identified more than 3000 novel transcription start sites (TSS) that are epigenetically regulated, most of which are derived from TE sequences.

Free Research Field

植物遺伝学

Academic Significance and Societal Importance of the Research Achievements

これまで理解されていなかった植物ゲノムにおける遺伝子の転写開始点制御と転移因子配列のエピジェネティック制御について本研究成果から明らかになった。