2021 Fiscal Year Final Research Report
Analysis of ER membrane proteins involved in ER morphogenesis in plant cells
| Project/Area Number |
19K06732
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 44030:Plant molecular biology and physiology-related
|
|---|
| Research Institution | Konan University |
|---|
Principal Investigator |
Ueda Haruko 甲南大学, 理工学部, 准教授 (90402776)
|
|---|
| Project Period (FY) |
2019-04-01 – 2022-03-31
|
| Keywords | 小胞体 / シロイヌナズナ / 膜タンパク質 |
|---|
| Outline of Final Research Achievements |
The endoplasmic reticulum (ER) is a multifunctional organelle underlying biological activities. The ER cisternae and tubules generate a continuous network distributed throughout the cell. The characteristic morphology of the ER is widely conserved in eukaryotes, but it is unclear how it is maintained. In this study, analysis of the Arabidopsis mutants suggests that the ER membrane proteins play an important role in maintaining the ER membrane structure through interaction with some membrane proteins.
|
| Free Research Field |
植物細胞生物学
|
| Academic Significance and Societal Importance of the Research Achievements |
小胞体は，タンパク質や脂質の合成で中心的な役割を果たす細胞小器官である．その特徴的な網目構造を生み出す遺伝子に異常をもつと，植物や動物に生育不全や疾患をもたらすこともある．本研究から，1種類の膜タンパク質の欠損によって小胞体の膜構造が大きな影響を受けることがわかった．特に植物細胞では小胞体が活発に運動しているため，動物や酵母とは異なる制御システムをもっている可能性も考えられる．
|
