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2023 Fiscal Year Final Research Report

Analysis of parthenogenetic oogenesis in the water flea Daphnia pulex

Research Project

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Project/Area Number 19K06778
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 45010:Genetics-related
Research InstitutionHokkaido University

Principal Investigator

Hiruta Chizue  北海道大学, 理学研究院, 特別研究員(RPD) (20723018)

Project Period (FY) 2019-04-01 – 2024-03-31
Keywordsミジンコ / 単為生殖 / 減数分裂 / 生殖細胞形成 / ゲノム編集
Outline of Final Research Achievements

The water flea Daphnia pulex adopt parthenogenesis and sexual reproduction differentially in response to various environmental cues, resulting in the production of diploid offspring in both reproductive modes. Histological analysis revealed that the parthenogenetic D. pulex adopt “abortive meiosis”, which skips a part of the first meiosis. However, little is known about its molecular mechanism. In this study, I advance the research in the establishment of genome editing system, and the elucidation of molecular mechanism of parthenogenetic oogenesis.

Free Research Field

生殖発生生物学

Academic Significance and Societal Importance of the Research Achievements

本研究は、ミジンコを材料に、受精することなく卵が単独で発生する単為生殖という生殖様式の詳細を明らかにしようとするものである。本研究では、生殖細胞を形成する機構である減数分裂がどのように改変されることによって単為発生が可能になるのかを検証中であり、最終的には動物界でみられる単為生殖の獲得と進化に関する理解を深めることが期待される。

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Published: 2025-01-30  

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