2021 Fiscal Year Final Research Report
Population genetics of continuously distributed populations
| Project/Area Number |
19K06782
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 45010:Genetics-related
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | 集団遺伝 / 集団構造 / シミュレーション |
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| Outline of Final Research Achievements |
Living organisms inhabit a continuous space and maintain genetic diversity. In the current population genetic analysis, the originally continuously distributed population of organisms is approximated as a combination of discrete sub-populations. Does this method adequately represent the reality? In this study, I performed a simulation-based analysis to conduct these issues. The results showed that it is necessary to use a specific set of Fst statistics for measuring and interpreting population structure. Furthermore, the type of data must be taken into account. The use of genotyped data inevitably distorts the information, but this effect can be minimized by using appropriate methods of creating markers.
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| Free Research Field |
集団遺伝学
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| Academic Significance and Societal Importance of the Research Achievements |
生物の多様性は、そのゲノム多様性に起因している。ゲノム多様性は集団の構造や歴史に影響されるが、現在の解析方法では近似的解析であるため、本来の姿を適切に反映しているかどうかわからない部分がある。本研究ではシミュレーションを行って問題点の把握と解決策の提案を行った。集団構造の測定に用いられる統計量や解析に用いるデータが解析を歪ませうることを量的に明確に示したことは有意義である。さらにこれらの影響を避けるための方法を提案することで今後の研究に指針を提示したという意味を持つ
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