2023 Fiscal Year Final Research Report
Identification of risk factors for cerebral embolism in the left atrial appendage and development and validation of a preoperative planning system for closure procedures
| Project/Area Number |
19K08588
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 53020:Cardiology-related
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2024-03-31
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| Keywords | atrial appendage / cardiogenic stroke |
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| Outline of Final Research Achievements |
We developed software equipped with a "Virtual Transesophageal Echo View" function, aimed at preoperative planning and intraoperative support for percutaneous left atrial appendage closure using contrast-enhanced CT images. This software was completed and made available for distribution to surrounding institutions, and its use in this treatment was widely publicized in a review article (J Cardiol DOI 10.1016/j.jjcc.2020.04.007). Additionally, a multi-center study was conducted to verify differences in measurements between tests and examiners, as well as the depiction capability and measurement errors of the transesophageal echo section compared to the Virtual Transesophageal Echo View (Heart Vessels DOI: 10.1007/s00380-024-02360-2).
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| Free Research Field |
Cardiology
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| Academic Significance and Societal Importance of the Research Achievements |
臨床医のニーズに基づくインターフェイスを持つ安価で汎用性の高く、パーソナルコンピューターで稼動するソフトウエアであること、多施設試験で正確性や有用性を検討できていることの意義は高い。デバイス閉鎖術における術前・術中計画支援、治療成績向上、医師の負荷の軽減、患者へのインフォームドコンセントなどに役立つと考える。
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