2021 Fiscal Year Final Research Report
Analysis of the pathogenesis of pruritic skin diseases and prurirus focusing on basophils
| Project/Area Number |
19K08767
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 53050:Dermatology-related
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
YOKOEKI HIROO 東京医科歯科大学, 大学院医歯学総合研究科, 特任教授 (90210608)
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| Co-Investigator(Kenkyū-buntansha) |
宇賀神 つかさ 東京医科歯科大学, 医学部附属病院, 講師 (40581327)
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| Project Period (FY) |
2019-04-01 – 2022-03-31
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| Keywords | contact dermatitis / prurigo / Food allergy / basophil / contact dermatitis / atopic dermatitis / stat6 / Zn |
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| Outline of Final Research Achievements |
Anaphylaxis due to transdermal sensitization of protein antigens, such as wheat-dependent exercise-induced anaphylaxis due to percutaneous sensitization of hydrolyzed wheat, has become a social problem. This year, we analyzed the mechanism of immunotherapy by oral inoculation of food anaphylactic.
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| Free Research Field |
免疫アレルギー
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| Academic Significance and Societal Importance of the Research Achievements |
新規治療法を開発し、抗IgE抗体を用いた臨床研究を痒疹、食物アレルギー患者に試みていく。
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