Exploratory research on factors affecting ovarian reserve in patients with endometriosis

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K09767
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 56040:Obstetrics and gynecology-related
• Research Institution: Kindai University
• Principal Investigator: Isao Tsuji 近畿大学, 医学部, 非常勤講師 (20368335)
• Co-Investigator(Kenkyū-buntansha): 松村 謙臣 近畿大学, 医学部, 教授 (20452336)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: チョコレート嚢胞 / 妊孕性

Outline of Final Research Achievements

In this study, we investigated the effect of repeated cyst aspiration and dienogest combination therapy on the outcome of assisted reproductive technology (ART) in infertile patients with endometrioma. Although this study is currently in progress, it was found that this treatment does not affect the outcome of ART at this time. However, it may be useful for large endometrioma and repetitive ART unsuccessful cases, and it is important to select infertile patients with endometrioma who require intervention.

Free Research Field

生殖医療

Academic Significance and Societal Importance of the Research Achievements

嚢胞反復穿刺吸引術とジェノゲスト併用療法は卵巣予備能を低下させることなくチョコレート嚢胞を治療できるため、チョコレート嚢胞合併不妊患者に対する新たな治療戦略のひとつとなりうる。また、将来の妊娠を希望する未婚女性に本治療を適用すれば、少子化対策に貢献できる。