Epidemiology of Escherichia albertii

2023 Fiscal Year Final Research Report

• Project/Area Number: 19K10590
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58020:Hygiene and public health-related: including laboratory approach
• Research Institution: Jumonji University (2022-2023); National Institute of Infectious Diseases (2019-2021)
• Principal Investigator: Murakami Koichi 十文字学園女子大学, 人間生活学部, 教授 (70446839)
• Co-Investigator(Kenkyū-buntansha): 重村 洋明 福岡県保健環境研究所, その他部局等, 研究員 (50761540)
• Project Period (FY): 2019-04-01 – 2024-03-31
• Keywords: Escherichia albertii / Food pathogen / Epidemiology

Outline of Final Research Achievements

We propose that nonbiogroup 1 or 2 of E. albertii should be assigned to biogroup 3 to make screening of them easier in public health and clinical laboratory settings. Clearly, having group criteria for indole-negative/lysine-positive, indole-positive/lysine-negative, and indolepositive/lysine-positive E. albertii biogroups 1, 2, and 3 strains, respectively, should provide for more accurate identification of E. albertii isolates. According to our study, the most common symptom displayed by patients across the six episodes was watery diarrhea (>80%), followed by abdominal pain (50-84%) and fever (37-39.5°c) (26-44%). The estimated average incubation period of E. albertii infection was 12-24 h. Three of the six outbreak associated E. albertii isolates possessed intact ETT2 regions, while the remaining isolates contained disrupted ETT2-encoding genes.
We found that E. albertii expressed flagella under specific environmental conditions.

Free Research Field

公衆衛生学

Academic Significance and Societal Importance of the Research Achievements

人獣共通感染症原因菌 Escherichia albertii の　①生物型分類の整理・提唱、②本菌食中毒の原因食品、潜伏期間等の疫学情報の提供、③本菌の鞭毛発現条件の発見、④本菌の薬剤耐性の状況の報告、⑤本菌の分離条件等を行い、本菌の疫学的な実態を多少なりとも明らかにしたと考える。