Epidemiological studies on the long-term prognosis of antiphospholipid antibody syndrome patients using a large-scale receipt data

2021 Fiscal Year Final Research Report

• Project/Area Number: 19K10619
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
• Research Institution: Kyoto University (2020-2021); Shiga University of Medical Science (2019)
• Principal Investigator: Tanaka Sachiko 京都大学, 医学研究科, 特定教授 (50453824)
• Project Period (FY): 2019-04-01 – 2022-03-31
• Keywords: 薬剤疫学

Outline of Final Research Achievements

Antiphospholipid syndrome (APS) is a disease which causes various thrombosis by failure and activation related to the autoantibody. For patients with APS, there are few epidemiological studies evaluating the prevalence of patients with APS and the long-term prognosis in the general population, although basic research and therapeutic evaluation have been conducted. We conducted the descriptive epidemiology of the treatment in the APS patient using the large-scale claim database. The result was presented in Asia Conference of Pharmacoepidemiology and Conference of Japanese Epidemiology Association. Additonally, the results were publishe in the international journal of pharmacoepidemiology.

Free Research Field

薬剤疫学

Academic Significance and Societal Importance of the Research Achievements

APS患者は希少疾患であり、一般集団におけるAPS患者の有病割合や血栓症発症などの長期予後を評価した疫学研究は少ない。本課題では大規模レセプトデータベースを用いて、APS患者における臨床疫学研究を実施を行い、実臨床への情報提供を行うことができたと考える。