2023 Fiscal Year Final Research Report
The effects of resistance training on pyruvate oxidation in mitochondria.
| Project/Area Number |
19K11521
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Review Section |
Basic Section 59020:Sports sciences-related
|
|---|
| Research Institution | Osaka Kyoiku University |
|---|
Principal Investigator |
ENOKI Taisuke 大阪教育大学, 教育学部, 准教授 (70392701)
|
|---|
| Project Period (FY) |
2019-04-01 – 2024-03-31
|
| Keywords | エネルギー代謝 / ミトコンドリア / レジスタンストレーニング / ピルビン酸 / 骨格筋 / 乳酸 |
|---|
| Outline of Final Research Achievements |
This study investigated whether the pyruvate produced by high muscle exertion (resistance & strength training), especially when the glycolytic pathway is activated, also affects the glycoxidative pathway in mitochondria.The results showed that the PDH enzyme that imports pyruvate into the mitochondria was increased and its activity was also upregulated.In addition, the enzyme that regulates PDH activity also increased.
These findings suggest that muscle strength training may affect not only the glycolytic but also the glycoxidative pathway.
|
| Free Research Field |
運動生理生化学、健康科学、スポーツ科学
|
| Academic Significance and Societal Importance of the Research Achievements |
高強度の筋収縮を特徴とする筋力トレーニングは、筋肥大や筋力発揮を主な目的とするが、エネルギー代謝の観点からみると、特に解糖系代謝を活性化させ、糖酸化系代謝の動員は少ない。しかし、本研究の結果から、筋力トレーニングは糖酸化系の酵素にも少なからず影響を与えており、スポーツ科学におけるトレーニングや健康科学分野における運動療法へと応用の可能性を示唆するものと考えられる。
|
