Introduction of different atoms into the metal nanoparticle surface and highly efficient transformation of organic molecules by their concerted catalysis

2020 Fiscal Year Final Research Report

• Project/Area Number: 19K15362
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 27030:Catalyst and resource chemical process-related
• Research Institution: Tokyo Metropolitan University
• Principal Investigator: Miura Hiroki 東京都立大学, 都市環境科学研究科, 助教 (20633267)
• Project Period (FY): 2019-04-01 – 2021-03-31
• Keywords: 担持金属触媒 / 金属ナノ粒子 / 有機合成 / 協奏的触媒作用

Outline of Final Research Achievements

Concerted catalytic function of different metals attracts much attention since they can realize unpreceded molecular transformations. In the present study, we found that ZrO2-supported PdAu alloy nanoparticle catalysts showed high activity for selective silylation of aryl chlorides to give the corresponding arylsilanes in high yields. While monometallic Pd and Au nanoparticles showed no activity for silylation of aryl chlorides, alloying Au and Pd significantly enhanced catalytic activity, and the reaction by Au-rich PdAu alloy nanoparticles gave arylsilanes with high selectivity. Furthermore, Au nanoparticles supported on TiO2 showed high catalytic activity for borylation of sp3 C-O bond to afford value-added organoboron compounds. A variety of allyl, propargyl and benzyl substrates participated in the heterogeneously catalyzed reactions to furnish the corresponding allyl, allenyl and benzyl boronates in high yields.

Free Research Field

触媒化学

Academic Significance and Societal Importance of the Research Achievements

本研究成果は、環境負荷の少ないグリーンな有機合成を実現するために化学的安定性が高く、再利用が可能、有害な金属の生成物への混入が少ないなどの利点を有する固体触媒の高機能化指針に資するものである。なかでも本研究で開発に成功した固体触媒による炭素-ケイ素、炭素-ホウ素結合形成反応は、有機合成のなかでも特に重要な合成中間体である有機ケイ素化合物、有機ホウ素化合物の実用的な合成を可能とする手法となりうるものであり、これにより医薬・農薬などの機能性有機分子の研究開発の加速が期待される。