Target-recogniging hydrogel photonic sensors using phase transitions in phospholipid membranes

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K15378
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 28010:Nanometer-scale chemistry-related
• Research Institution: Tokyo University of Agriculture and Technology (2020-2022); Institute of Physical and Chemical Research (2019)
• Principal Investigator: Uchida Noriyuki 東京農工大学, 工学(系)研究科(研究院), 特任助教 (20782204)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: フォトニック結晶 / リン脂質膜

Outline of Final Research Achievements

In this research project, dynamic photonic crystals made of phospholipids were prepared with the aim of developing a highly sensitive sensor based on structural colour change using phase transitions in phospholipid membranes. The preparation method of the phospholipid membrane photonic crystals was optimised and the basic properties of their stimulus responsiveness were evaluated. The biocompatibility of the dynamic photonic crystals was evaluated with a view to their application as wearable sensors.

Free Research Field

バイオマテリアル

Academic Significance and Societal Importance of the Research Achievements

本研究結果は市販で購入可能なリン脂質からなる高感度フォトニック結晶の作成に成功しており、実用性、および生体親和性が極めて高い材料を実現することができた。また、標的に応じて受容体分子を変化させることで、様々な標的に対する高感度センサーを作成することができるため、汎用性が高いセンサー材料である。