2020 Fiscal Year Final Research Report
Catalytic Synthesis of Organic Compounds Containing Nitrogen via Transformation of N-N bond
Project/Area Number |
19K15551
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 33020:Synthetic organic chemistry-related
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Research Institution | Tohoku University |
Principal Investigator |
Tanii Saori 東北大学, 薬学研究科, 助教 (20792295)
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Project Period (FY) |
2019-04-01 – 2021-03-31
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Keywords | アゾ化合物 / ジホスフィン化合物 / ロジウム触媒 / 多縮環芳香環エーテル / 酸触媒 |
Outline of Final Research Achievements |
It is expected that development of new synthetic method of compounds containing N-X (X = C, heteroatom) bond without going through amines is expected, because synthesis pathway can be simplified, and compounds synthesized hardly can be synthesized. I found that one P atom of diphosphine P-P bond could addition to N=N bond of azoarenes by transition-metal catalysis, and various new compounds containing P-N-N-H bond could be synthesized. It is first example that P atom of P-P bond addition to N=N bond by transition metal catalyst and this is new synthetic method. In addition, I achieved that polycyclic aromatic ethers could be synthesized from polycyclic aromatic alcohols by acid catalyst. General synthesis methods of polycyclic aromatic ethers have not been found and I think this result can lead to development of electronic and optical chemistry of polycyclic aromatic compounds.
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Free Research Field |
有機化学
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Academic Significance and Societal Importance of the Research Achievements |
アゾベンゼン誘導体 N=N 結合の遷移金属触媒的変換反応は比較的少なく、これらは配向基として利用されることが多かった。遷移金属触媒的にこれを変換でき、N-P 結合を合成できたことは、この結果を皮切りに、N=N 結合の新規変換反応につながる可能性を示すと考えられる。また、アミンを経由しない N=N 結合から N-X (X = C, heteroatom) 結合への触媒的な変換は、省エネルギー的な反応であるため、環境調和型の反応といえる。加えて、この反応を発展させることで、N=N 結合に類似した結合を有する窒素分子の活性化反応にもつながると考えている。
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