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2020 Fiscal Year Final Research Report

Establishment of the basic technology for producing Z-isomer-rich carotenoid material having high bioavailability and excellent processability

Research Project

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Project/Area Number 19K15779
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 38050:Food sciences-related
Research InstitutionMeijo University

Principal Investigator

Honda Masaki  名城大学, 理工学部, 助教 (60824191)

Project Period (FY) 2019-04-01 – 2021-03-31
Keywordsカロテノイド / 異性化 / 抽出 / 安定化 / 天然触媒 / イソチオシアネート類 / ポリスルフィド類
Outline of Final Research Achievements

Carotenoids are important natural compounds used in food and cosmetic industries, and are generally obtained from plants and microorganisms by solvent extraction. However, natural carotenoids (all-E-isomer) have low solubility in various solvents, and that results in low production efficiency of them via the extraction method. Here, we developed a novel Z-isomerization technology of carotenoids using natural catalysts, and utilizing the changes in physical properties associated with the isomerization, an efficient method for carotenoid extraction was developed. In addition, a stabilization technology of Z-isomer-rich carotenoids was also developed aiming at practical applications.

Free Research Field

食品科学

Academic Significance and Societal Importance of the Research Achievements

これまで、天然のカロテノイド(トランス型)をシス型に変換するためには、高温処理や重金属触媒の利用が不可欠であった。今回、イソチオシアネート類やポリスルフィド類など、天然由来の有機分子がカロテノイド異性化反応の触媒効果を示すことを明らかにした。本知見を活用することで、シス型比率を高めたカロテノイド素材の効率的な製造が可能になる。さらに、異性化に伴う物性改変を活用することでカロテノイド素材の生産効率を改善できることを明らかにし、シス型カロテノイドを安定化できる処方を開発した。これらの成果は、カロテノイド素材の高付加価値化と低価格化につながる重要な知見である。

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Published: 2022-01-27  

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