2019 Fiscal Year Research-status Report
SynNotch EV cells-flexible ”CAR T”-cells
| Project/Area Number |
19K16849
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| Research Institution | National Center of Neurology and Psychiatry |
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Principal Investigator |
NORDIN JOEL 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 遺伝子疾患治療研究部, 客員研究員 (70836064)
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| Project Period (FY) |
2019-04-01 – 2021-03-31
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| Keywords | Immunology / Muscle / CART / Gene therapy |
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| Outline of Annual Research Achievements |
The aim of this project is to utilise Syn-Notch EV cells to deliver macromolecular to cells. EVs have been shown to be able to transfer macromolecules to cells. Syn-Notch EV cells would deliver engineered EVs to specific cells after activation of the Syn-Notch receptor by a user defined antigen.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
I am proceeding study according to plan.
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| Strategy for Future Research Activity |
I am planning to test whether the Syn-Notch EV cells could deliver engineered EVs to specific cells after activation of the Syn-Notch receptor by a user defined antigen.
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Research Products
(2 results)
