Research on prediction of prognosis in adolescent patients with psychiatric disorders using electroencephalogram (EEG) as an indicator

2022 Fiscal Year Final Research Report

• Project/Area Number: 19K17105
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 52030:Psychiatry-related
• Research Institution: The University of Tokyo
• Principal Investigator: Tada Mariko 東京大学, 相談支援研究開発センター, 講師 (70758193)
• Project Period (FY): 2019-04-01 – 2023-03-31
• Keywords: 精神疾患 / 脳波

Outline of Final Research Achievements

We measured EEG (MMN and ASSR) and assessed clinical symptoms and social functioning in study participants with a diagnosis of F2, F3, or F4 on the ICD-10 from their attending psychiatrists among adolescents. A literature review (Tada et al., 2019; Tada etal., 2020.) was conducted on the significance of changes in MMN and ASSR in adolescents with psychiatric disorders. To further examine the relationship between ASSR and pathophysiology, we investigated the source and found that a network extending from the auditory cortex to the extrasensory cortex is involved (Tada et al., 2021).

Free Research Field

精神医学

Academic Significance and Societal Importance of the Research Achievements

精神疾患の発症時期である思春期の患者において、脳波指標（MMNとASSR）の変化の意義と病態の関連を明らかにした。特に、ASSRの発生源に、従来考えられていたよりも広範囲のネットワークが関与することを明らかにしたことは、臨床像からの早期診断が難しい精神疾患の早期病態の理解や治療開発に貢献することが期待できる。