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2020 Fiscal Year Annual Research Report

Comprehensive 4D Flow MRI assessment for hypertrophic obstructive cardiomyopathy

Research Project

Project/Area Number 19K17151
Research InstitutionNippon Medical School

Principal Investigator

関根 鉄朗  日本医科大学, 医学部, 講師 (00747826)

Project Period (FY) 2019-04-01 – 2021-03-31
Keywords4D Flow MRI / CFD / HCM / energy loss / Turbulent kinetic energy / pressure loss / aortic stenosis / MRI
Outline of Annual Research Achievements

肥大型心筋症に対する4D Flow MRIを用いた圧較差推定法について、種々の手法を比
較検討し、頑強な測定手法を開発した。無症候の肥大型心筋症患者において、4D Flow MRIで計測した圧較差が
心筋重量と良好に相関する事を明らかにし、更なる病態の層別化に本手法が有用な可能性を示した。更に、本手法を発展させ、大動脈解離術後患者に対して応用を行い、外科手術後の残存解離喰う拡張とTKEの良好な相関を確認した。
詳細は研究成果報告書を参照の事。

  • Research Products

    (22 results)

All 2021 2020

All Journal Article (11 results) Presentation (7 results) (of which Int'l Joint Research: 1 results,  Invited: 7 results) Book (4 results)

  • [Journal Article] Harmonized pretreatment quantitative volume-based FDG-PET/CT parameters for prognosis of stage I-III breast cancer: Multicenter study2021

    • Author(s)
      Kitajima Kazuhiro、Miyoshi Yasuo、Sekine Tetsuro、Takei Hiroyuki、Ito Kimiteru、Suto Akihiko、Kaida Hayato、Ishii Kazunari、Daisaki Hiromitsu、Yamakado Koichiro
    • Journal Title

      Oncotarget

      Volume: 12 Pages: 95~105

    • DOI

      10.18632/oncotarget.27851

  • [Journal Article] Careful consideration should be paid in the new imaging modality evaluation2021

    • Author(s)
      Sekine Tetsuro、Nakaza Masatoki、Kumita Shinichiro
    • Journal Title

      Journal of Thoracic Disease

      Volume: 13 Pages: 422~424

    • DOI

      10.21037/jtd-20-3229

  • [Journal Article] Dual-VENC 4D Flow MRI Can Detect Abnormal Blood Flow in the Left Atrium That Potentially Causes Thrombosis Formation after Left Upper Lobectomy2021

    • Author(s)
      Nakaza Masatoki、Matsumoto Mitsuo、Sekine Tetsuro、Inoue Tatsuya、Ando Takahiro、Ogawa Masashi、Obara Makoto、Leonowicz Olgierd、Kumita Shinichiro、Usuda Jitsuo
    • Journal Title

      Magnetic Resonance in Medical Sciences

      Volume: ** Pages: **

    • DOI

      10.2463/mrms.mp.2020-0170

  • [Journal Article] Four-dimensional flow magnetic resonance imaging reveals the reduction in turbulent kinetic energy after percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy2020

    • Author(s)
      Iwata Kotomi、Matsuda Junya、Imori Yoichi、Sekine Tetsuro、Takano Hitoshi
    • Journal Title

      European Heart Journal

      Volume: 41 Pages: 1454~1454

    • DOI

      10.1093/eurheartj/ehz618

  • [Journal Article] 4D Flow MR Imaging Reveals a Decrease of Left Atrial Blood Flow in a Patient with Cardioembolic Cerebral Infarction after Pulmonary Left Upper Lobectomy2020

    • Author(s)
      Matsumoto Mitsuo、Takegahara Kyoshiro、Inoue Tatsuya、Nakaza Masatoki、Sekine Tetsuro、Usuda Jitsuo
    • Journal Title

      Magnetic Resonance in Medical Sciences

      Volume: 19 Pages: 290~293

    • DOI

      10.2463/mrms.ici.2019-0142

  • [Journal Article] Critical Review of the Literature on Chest CT and Coronavirus Disease (COVID-19): Data Adjustment2020

    • Author(s)
      Sekine Tetsuro
    • Journal Title

      American Journal of Roentgenology

      Volume: 215 Pages: W27~W27

    • DOI

      10.2214/AJR.20.23435

  • [Journal Article] Factors associated with prolonged surgical duration of laparoscopic radical nephrectomy using retroperitoneal approach by non-expert surgeons2020

    • Author(s)
      Yanagi Masato、Kimura Go、Sekine Tetsuro、Takeda Hayato、Akatsuka Jun、Endo Yuki、Hayashi Tatsuro、Hamasaki Tsutomu、Kondo Yukihiro
    • Journal Title

      Journal of Nippon Medical School

      Volume: ** Pages: **

    • DOI

      10.1272/jnms.JNMS.2021_88-302

  • [Journal Article] The impact of atlas-based MR attenuation correction on the diagnosis of FDG-PET/MR for Alzheimer’s diseases? A simulation study combining multi-center data and ADNI-data2020

    • Author(s)
      Sekine Tetsuro、Buck Alfred、Delso Gaspar、Kemp Bradley、ter Voert Edwin E. G. W.、Huellner Martin、Veit-Haibach Patrick、Kaushik Sandeep、Wiesinger Florian、Warnock Geoffrey、for the Alzheimer’s Disease Neuroimaging Initiative
    • Journal Title

      PLOS ONE

      Volume: 15 Pages: **

    • DOI

      10.1371/journal.pone.0233886

  • [Journal Article] Multiparametric flow analysis using four-dimensional flow magnetic resonance imaging can detect cerebral hemodynamic impairment in patients with internal carotid artery stenosis2020

    • Author(s)
      Ando Takahiro、Sekine Tetsuro、Murai Yasuo、Orita Erika、Takagi Ryo、Amano Yasuo、Iwata Kotomi、Nakaza Masatoki、Ogawa Masashi、Obara Makoto、Kumita Shin-ichiro
    • Journal Title

      Neuroradiology

      Volume: 62 Pages: 1421~1431

    • DOI

      10.1007/s00234-020-02464-2

  • [Journal Article] Turbulent Kinetic Energy Is Different from Viscous Energy Loss2020

    • Author(s)
      Iwata Kotomi、Sekine Tetsuro、Tanaka Izumi、Ando Takahiro、Orita Erika
    • Journal Title

      RadioGraphics

      Volume: 40 Pages: 2142~2144

    • DOI

      10.1148/rg.2020200177

  • [Journal Article] Zero Echo Time MRAC on FDG-PET/MR Maintains Diagnostic Accuracy for Alzheimer’s Disease; A Simulation Study Combining ADNI-Data2020

    • Author(s)
      Ando Takahiro、Kemp Bradley、Warnock Geoffrey、Sekine Tetsuro、Kaushik Sandeep、Wiesinger Florian、Delso Gaspar
    • Journal Title

      Frontiers in Neuroscience

      Volume: 14 Pages: **

    • DOI

      10.3389/fnins.2020.569706

  • [Presentation] 脳血管の4D Flow MRI -いつ始めるか? 今でしょ!- (招待講演 60分)2021

    • Author(s)
      関根鉄朗
    • Organizer
      第 12 回 「MRI を究める学術集会:信州 MRI・技術と臨床」
    • Invited
  • [Presentation] 4D Flow MRIを用いた乱流運動エネルギー推定と心大血管血流評価 (招待講演, 30分, 日本語)2020

    • Author(s)
      関根鉄朗
    • Organizer
      京都府立大学 放射線科 デイリーカンファレンス
    • Invited
  • [Presentation] 4D Flow MRIの臨床応用. (招待講演, 50分, 日本語, web開催)2020

    • Author(s)
      関根鉄朗
    • Organizer
      Stroke 2020
    • Invited
  • [Presentation] Non-Contrast-Enhanced MRI in Stroke. (Educational lecture, 30 minutes)2020

    • Author(s)
      関根鉄朗
    • Organizer
      国際磁気共鳴学会
    • Int'l Joint Research / Invited
  • [Presentation] 4D Flow MRIで見た心筋疾患 血流解析の最先端:血流会 meet JCS 2020. (招待講演, 15分, 日本語, web開催)2020

    • Author(s)
      関根鉄朗
    • Organizer
      第84回日本循環器学会学術集会 2020年7月
    • Invited
  • [Presentation] Airロードショー (依頼講演, 講師, 55分, 日本語)2020

    • Author(s)
      関根鉄朗
    • Organizer
      Airロードショー
    • Invited
  • [Presentation] 4D Flow MRIで見るマクロからミクロな動き -乱流運動エネルギー定量の原理と臨床応用 (依頼講演, 講師, 55分, 日本語)2020

    • Author(s)
      関根鉄朗
    • Organizer
      第15回動態機能研究会
    • Invited
  • [Book] 新核医学技術総論2020

    • Author(s)
      関根鉄朗
    • Total Pages
      **
    • Publisher
      山代印刷出版部
  • [Book] PET/MRIの臨床2020

    • Author(s)
      関根鉄朗
    • Total Pages
      **
    • Publisher
      診断と治療社
  • [Book] Neuroimaging Techniques in Clinical Practice: Physical Concepts and Clinical Applications2020

    • Author(s)
      関根鉄朗
    • Total Pages
      **
    • Publisher
      Springer International Publishing
  • [Book] Diagnostic Imaging in Head and Neck Cancer2020

    • Author(s)
      関根鉄朗
    • Total Pages
      **
    • Publisher
      Springer International Publishing

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Published: 2021-12-27  

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