• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2019 Fiscal Year Research-status Report

Toxicity Reduction with Antifungal Prophylaxis during Chemoradiotherapy for Head and Neck Cancer

Research Project

Project/Area Number 19K17262
Research InstitutionNiigata University

Principal Investigator

齋藤 紘丈  新潟大学, 医歯学総合病院, 特任助教 (90750315)

Project Period (FY) 2019-04-01 – 2023-03-31
Keywords倫理審査 / データマネジメント準備 / 後方視的研究
Outline of Annual Research Achievements

臨床研究推進センターとデータマネジメントに関する契約を行った。また、研究室にワークステーションを設置し、中央臨床研究審査委員会にて審議を受けた。すべてそれらに科研費を充当した。当該臨床試験の根拠となる後方視的研究(Saito H, Shodo R, Yamazaki K, Katsura K, Ueki Y, Nakano T, Oshikane T, Yamana N, Tanabe S, Utsunomiya S, Ohta A, Abe E, Kaidu M, Sasamoto R, Aoyama H: The association between oral candidiasis and severity of chemoradiotherapy-induced dysphagia in head and neck cancer patients: A retrospective cohort study. Clin Transl Radiat Oncol 20:13-18,2019)を、英文誌に投稿し受理された。また、悪性神経膠腫のIMRT(強度変調放射線治療)の適応基準に関する共著の英文論文も採択された(Tanabe S, Takahashi H, Saito H, Ohta A, Nakano T, Sasamoto R, Shioi M, Utsunomiya S, Abe E, Kaidu M, Aoyama H: Selection criteria for 3D conformal radiotherapy versus volumetric-modulated arc therapy in high-grade glioma based on normal tissue complication probability of brain. J Radiat Res 60(2):249-256,2019)。初年度としては、大きな研究成果であると考えられる。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

臨床試験の準備としては、順調に推移している。また、英文誌に論文が掲載されたため。

Strategy for Future Research Activity

フルコナゾールを研究費にて購入し、臨床研究推進センターで保管いただく。7月以降、症例登録を進める。

Causes of Carryover

次年度の薬剤購入などに充当する予定。

  • Research Products

    (4 results)

All 2020 2019

All Journal Article (4 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] The association between oral candidiasis and severity of chemoradiotherapy-induced dysphagia in head and neck cancer patients: A retrospective cohort study2020

    • Author(s)
      H. Saito, R. Syoudo, K. Yamazaki, H. Aoyama et al.
    • Journal Title

      Clinical and Translational Radiation Oncology

      Volume: 20 Pages: 13-18

    • DOI

      10.1016/j.ctro.2019.10.006.

    • Peer Reviewed / Open Access
  • [Journal Article] The neurocognitive function change criteria after whole-brain radiation therapy for brain metastasis, in reference to health-related quality of life changes: a prospective observation study2020

    • Author(s)
      Nakano Toshimichi、Aoyama Hidefumi、Saito Hirotake、Tanabe Satoshi、Tanaka Kensuke、Maruyama Katsuya、Oshikane Tomoya、Ohta Atsushi、Abe Eisuke、Kaidu Motoki
    • Journal Title

      BMC Cancer

      Volume: 20 Pages: 66~76

    • DOI

      10.1186/s12885-020-6559-3

  • [Journal Article] Selection criteria for 3D conformal radiotherapy versus volumetric-modulated arc therapy in high-grade glioma based on normal tissue complication probability of brain2019

    • Author(s)
      Tanabe Satoshi、Takahashi Haruna、Saito Hirotake、Ohta Atsushi、Nakano Toshimichi、Sasamoto Ryuta、Shioi Miki、Utsunomiya Satoru、Abe Eisuke、Kaidu Motoki、Aoyama Hidefumi
    • Journal Title

      Journal of Radiation Research

      Volume: 60 Pages: 249~256

    • DOI

      10.1093/jrr/rry106

  • [Journal Article] Dramatic response of BRAF V600E-mutant epithelioid glioblastoma to combination therapy with BRAF and MEK inhibitor: establishment and xenograft of a cell line to predict clinical efficacy2019

    • Author(s)
      Kanemaru Yu、Natsumeda Manabu、Okada Masayasu、Saito Rie、Kobayashi Daiki、Eda Takeyoshi、Watanabe Jun、Saito Shoji、Tsukamoto Yoshihiro、Oishi Makoto、Saito Hirotake、Nagahashi Masayuki、Sasaki Takahiro、Hashizume Rintaro、Aoyama Hidefumi、Wakai Toshifumi、Kakita Akiyoshi、Fujii Yukihiko
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 7 Pages: 119~129

    • DOI

      10.1186/s40478-019-0774-7

URL: 

Published: 2021-01-27  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi